Immunofixation (IFE) Idanwo Ẹjẹ

Akoonu

• Kini idanwo ẹjẹ ti ajẹsara (IFE)?
• Kini o ti lo fun?
• Kini idi ti MO nilo idanwo IFE?
• Kini yoo ṣẹlẹ lakoko idanwo IFE?
• Ṣe Mo nilo lati ṣe ohunkohun lati mura fun idanwo naa?
• Ṣe awọn eewu eyikeyi wa si idanwo IFE?
• Kini awọn abajade tumọ si?
• Njẹ ohunkohun miiran ti Mo nilo lati mọ nipa idanwo IFE kan?
• Awọn itọkasi

Kini idanwo ẹjẹ ti ajẹsara (IFE)?

Idanwo ẹjẹ ti ajẹsara, ti a tun mọ ni electrophoresis amuaradagba, ṣe iwọn awọn ọlọjẹ kan ninu ẹjẹ. Awọn ọlọjẹ ṣe ọpọlọpọ awọn ipa pataki, pẹlu pipese agbara fun ara, atunkọ awọn iṣan, ati atilẹyin eto aarun.

Awọn oriṣi akọkọ meji ti awọn ọlọjẹ wa ninu ẹjẹ: albumin ati globulin. Idanwo naa ya awọn ọlọjẹ wọnyi si awọn ẹgbẹ-ẹgbẹ ti o da lori iwọn wọn ati idiyele itanna. Awọn ẹgbẹ kekere ni:

• Albumin
• Alpha-1 globulin
• Alpha-2 globulin
• Beta globulin
• Gamma globulin

Wiwọn awọn ọlọjẹ ninu ẹgbẹ-ẹgbẹ kọọkan le ṣe iranlọwọ iwadii ọpọlọpọ awọn aisan.

Awọn orukọ miiran: amọradagba electrophoresis, (SPEP), electrophoresis amuaradagba, SPE, electrophoresis imunofixation, IFE, imunofixation omi ara

Kini o ti lo fun?

Idanwo yii ni igbagbogbo lo lati ṣe iranlọwọ iwadii tabi ṣetọju ọpọlọpọ awọn ipo oriṣiriṣi. Iwọnyi pẹlu:

• Ọpọ myeloma, akàn ti awọn sẹẹli ẹjẹ funfun
• Awọn ọna miiran ti aarun, gẹgẹbi lymphoma (akàn ti eto ara) tabi aisan lukimia (akàn ti awọn ara ti o ni ẹjẹ, gẹgẹbi ọra inu egungun)
• Àrùn Àrùn
• Ẹdọ ẹdọ
• Awọn arun autoimmune kan ati awọn rudurudu ti iṣan
• Aito ibajẹ tabi malabsorption, awọn ipo eyiti ara rẹ ko ni awọn ounjẹ to to lati awọn ounjẹ ti o jẹ

Kini idi ti MO nilo idanwo IFE?

O le nilo idanwo ti o ba ni awọn aami aiṣan ti awọn aisan kan, gẹgẹbi myeloma lọpọlọpọ, ọpọ sclerosis, aijẹ aito, tabi malabsorption.

Awọn aami aisan ti myeloma ọpọ pẹlu:

• Egungun irora
• Rirẹ
• Ẹjẹ (ipele kekere ti awọn sẹẹli ẹjẹ pupa)
• Awọn àkóràn loorekoore
• Ongbe pupọ
• Ríru

Awọn aami aisan ti ọpọlọ-ọpọlọ ọpọ pẹlu:

• Nọnju tabi fifun ni oju, apa ati / tabi ese
• Iṣoro rin
• Rirẹ
• Ailera
• Dizziness ati vertigo
• Awọn iṣoro ṣiṣakoso ito

Awọn aami aisan ti aijẹ aito tabi malabsorption pẹlu:

• Ailera
• Rirẹ
• Pipadanu iwuwo
• Ríru ati eebi
• Egungun ati irora apapọ

Kini yoo ṣẹlẹ lakoko idanwo IFE?

Onimọṣẹ ilera kan yoo mu ayẹwo ẹjẹ lati iṣọn kan ni apa rẹ, ni lilo abẹrẹ kekere kan. Lẹhin ti a fi sii abẹrẹ, iye ẹjẹ kekere yoo gba sinu tube idanwo tabi igo kan. O le ni irọra diẹ nigbati abẹrẹ ba wọ inu tabi jade. Eyi maa n gba to iṣẹju marun.

Ṣe Mo nilo lati ṣe ohunkohun lati mura fun idanwo naa?

O ko nilo awọn ipese pataki eyikeyi fun idanwo ẹjẹ ajẹsara.

Ṣe awọn eewu eyikeyi wa si idanwo IFE?

Ewu pupọ wa si nini idanwo ẹjẹ. O le ni irora diẹ tabi ọgbẹ ni aaye ibiti a ti fi abẹrẹ sii, ṣugbọn ọpọlọpọ awọn aami aisan lọ ni kiakia.

Kini awọn abajade tumọ si?

Awọn abajade rẹ yoo fihan pe awọn ipele amuaradagba rẹ wa ni ibiti o ṣe deede, ti o ga julọ, tabi ti o kere ju.

Awọn ipele amuaradagba giga le fa nipasẹ ọpọlọpọ awọn ipo. Awọn idi ti o wọpọ ti awọn ipele giga pẹlu:

• Gbígbẹ
• Ẹdọ ẹdọ
• Awọn aarun iredodo, ipo kan nigbati eto alaabo ara kolu awọn tisọ ilera ni aṣiṣe. Awọn aarun iredodo pẹlu arun ara ọgbẹ ati arun Crohn. Awọn arun iredodo jẹ iru si awọn aarun autoimmune, ṣugbọn wọn ni ipa awọn oriṣiriṣi awọn ẹya ti eto alaabo.
• Àrùn Àrùn
• Idaabobo giga
• Aito ẹjẹ-aini-iron
• Ọpọ myeloma
• Lymphoma
• Awọn akoran kan

Awọn ipele amuaradagba kekere le fa nipasẹ ọpọlọpọ awọn ipo. Awọn idi ti o wọpọ ti awọn ipele kekere pẹlu:

• Àrùn Àrùn
• Ẹdọ ẹdọ
• Aini antitrypsin Alpha-1, rudurudu ti a jogun ti o le ja si arun ẹdọfóró ni ọjọ-ori
• Aijẹ aito
• Awọn aiṣedede autoimmune kan

Iwadii rẹ yoo dale lori iru awọn ipele amuaradagba kan pato ko ṣe deede, ati boya awọn ipele naa ti ga ju tabi ti kere ju. O tun le dale lori awọn ilana alailẹgbẹ ti awọn ọlọjẹ ṣe.

Ti o ba ni awọn ibeere nipa awọn abajade rẹ, sọrọ si olupese iṣẹ ilera rẹ.

Kọ ẹkọ diẹ sii nipa awọn idanwo yàrá, awọn sakani itọkasi, ati oye awọn abajade.

Njẹ ohunkohun miiran ti Mo nilo lati mọ nipa idanwo IFE kan?

Awọn idanwo imunofixation tun le ṣee ṣe ni ito. Ito IFE ito ni igbagbogbo ti awọn abajade idanwo ẹjẹ IFE ko ṣe deede.

Awọn itọkasi

1. Ilera Allina [Intanẹẹti]. Minneapolis: Ilera Allina; c2019. Amuaradagba electrophoresis-omi ara; [toka si 2019 Oṣu kejila 10]; [nipa iboju 3]. Wa lati: https://account.allinahealth.org/library/content/1/3540
2. Akàn.Net [Intanẹẹti]. Alexandria (VA): American Society of Clinical Oncology; 2005–2019. Myeloma lọpọlọpọ: Ayẹwo; 2018 Jul [toka 2019 Dec 10]; [nipa iboju 3]. Wa lati: https://www.cancer.net/cancer-types/multiple-myeloma/diagnosis
3. Akàn.Net [Intanẹẹti]. Alexandria (VA): American Society of Clinical Oncology; 2005–2019. Myeloma lọpọlọpọ: Awọn aami aisan ati Awọn ami; 2016 Oṣu Kẹwa [toka 2019 Dec 10]; [nipa iboju 3]. Wa lati: https://www.cancer.net/cancer-types/multiple-myeloma/symptoms-and-signs
4. Hinkle J, Cheever K. Brunner & Suddarth's Iwe amudani ti yàrá ati Awọn Idanwo Ayẹwo. 2nd Ed, Kindu. Philadelphia: Ilera Ilera Wolters, Lippincott Williams & Wilkins; c2014. Amuaradagba Electrophoresis; p. 430.
5. Awọn idanwo Lab lori Ayelujara [Intanẹẹti]. Washington DC: Association Amẹrika fun Kemistri Iṣoogun; c2001–2019. Alpha-1 Antitrypsin; [imudojuiwọn 2019 Nov 13; toka si 2019 Dec 10]; [nipa iboju 2]. Wa lati: https://labtestsonline.org/tests/alpha-1-antitrypsin
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Alaye lori aaye yii ko yẹ ki o lo bi aropo fun itọju iṣoogun ọjọgbọn tabi imọran. Kan si olupese ilera kan ti o ba ni awọn ibeere nipa ilera rẹ.