Acid acid

Lactic acidosis tọka si acid lactic ti o dagba ninu iṣan ẹjẹ. A ṣe iṣelọpọ Lactic acid nigbati awọn ipele atẹgun, di kekere ninu awọn sẹẹli laarin awọn agbegbe ti ara nibiti iṣelọpọ ti n ṣẹlẹ.

Idi ti o wọpọ julọ ti acidic lactic jẹ aisan iṣoogun ti o nira ninu eyiti titẹ ẹjẹ jẹ kekere ati pe atẹgun ti o kere pupọ n de awọn awọ ara. Idaraya kikankikan tabi awọn iwariri le fa idi igba diẹ laito acidosis. Awọn aisan kan tun le fa ipo naa pẹlu:

• Arun Kogboogun Eedi
• Ọti-lile
• Akàn
• Cirrhosis
• Majele ti Cyanide
• Ikuna ikuna
• Ikuna atẹgun
• Sepsis (ikolu to lagbara)

Diẹ ninu awọn oogun le ṣọwọn fa acidosis lactic:

• Awọn ifasimu kan lo lati tọju ikọ-fèé tabi COPD
• Efinifirini
• Ajẹsara ti a npe ni linezolid
• Metformin, lo lati ṣe itọju àtọgbẹ (igbagbogbo julọ nigbati o ba bori)
• Iru oogun kan ti a lo lati tọju arun HIV
• Propofol

Awọn aami aisan le pẹlu:

• Ríru
• Ogbe
• Ailera

Awọn idanwo le pẹlu idanwo ẹjẹ lati ṣayẹwo lactate ati awọn ipele itanna.

Itọju akọkọ fun acidic lactic ni lati ṣatunṣe iṣoro iṣoogun ti o fa ipo naa.

Palmer BF. Acidosis ti iṣelọpọ. Ni: Feehally J, Floege J, Tonelli, Johnson RJ, awọn eds. Okeerẹ Clinical Nephrology. 6th ed. Philadelphia, PA: Elsevier; 2019: ori 12.

Seifter JL. Awọn aiṣedede ipilẹ-acid. Ni: Goldman L, Schafer AI, awọn eds. Oogun Goldman-Cecil. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: ori 118.

Strayer RJ. Awọn aiṣedede ipilẹ-acid. Ninu: Odi RM, Hockberger RS, Gausche-Hill M, et al, eds. Oogun pajawiri ti Rosen: Awọn Agbekale ati Iwa-iwosan. 9th ed. Philadelphia, PA: Elsevier Saunders; 2018: ori 116.