Resveratrol
Onkọwe Ọkunrin:
William Ramirez
ỌJọ Ti ẸDa:
18 OṣU KẹSan 2021
ỌJọ ImudojuiwọN:
1 OṣU KẹRin 2025

Akoonu
- O ṣee ṣe ki o munadoko fun ...
- O ṣee ṣe ki o munadoko fun ...
- Ẹri ti ko to lati ṣe iṣiro oṣuwọn fun ...
- Awọn iṣọra pataki & awọn ikilo:
Resveratrol jẹ lilo pupọ julọ fun idaabobo awọ giga, akàn, aisan ọkan, ati ọpọlọpọ awọn ipo miiran. Sibẹsibẹ, ko si ẹri ti o lagbara lati ṣe atilẹyin fun lilo resveratrol fun awọn lilo wọnyi.
Awọn Ile-ẹkọ Iṣeduro Alaye Awọn Oogun Adayeba awọn oṣuwọn doko da lori ẹri ijinle sayensi ni ibamu si iwọn wọnyi: Imudara, O ṣeeṣe Ki o munadoko, O ṣeeṣe Ki o munadoko, O ṣeeṣe Ki o munadoko, O ṣeeṣe pe ko wulo, ko wulo, ati Ẹri ti ko to lati Oṣuwọn.
Awọn igbelewọn ṣiṣe fun RESVERATROL ni atẹle:
O ṣee ṣe ki o munadoko fun ...
- Iba. Lilo ifunra imu ti o ni resveratrol ni igba mẹta lojoojumọ fun ọsẹ mẹrin 4 dabi pe o dinku awọn aami aiṣan ti ara korira ninu awọn agbalagba pẹlu awọn nkan ti ara korira akoko. Lilo itọ imu ti o ni resveratrol ati beta-glucans ni igba mẹta lojoojumọ fun awọn oṣu 2 tun dabi pe o dinku awọn aami aiṣan ti ara korira ninu awọn ọmọde pẹlu awọn nkan ti ara korira akoko.
- Isanraju. Diẹ ninu iwadi ṣe afihan pe gbigba resveratrol le mu pipadanu iwuwo pọ si awọn agbalagba ti o sanra.
O ṣee ṣe ki o munadoko fun ...
- Arun okan. Awọn eniyan ti o gba iye ti o ga julọ ti resveratrol ti ounjẹ ko dabi pe o ni eewu kekere ti aisan ọkan ni akawe si awọn eniyan ti o jẹ iye kekere. Pẹlupẹlu, gbigba resveratrol nipasẹ ẹnu ko dabi lati mu awọn ipele ti idaabobo awọ pọ tabi awọn ọra ẹjẹ ti a pe ni triglycerides ninu awọn eniyan ti o wa ni eewu fun aisan ọkan.
- Kikojọ awọn aami aisan ti o mu eewu ti àtọgbẹ, arun ọkan, ati ikọlu ṣiṣẹ (iṣọn ara ijẹ-ara). Gbigba resveratrol ko dabi ẹni pe o dinku titẹ ẹjẹ, suga ẹjẹ, tabi idaabobo awọ ninu awọn eniyan ti o ni iṣọn ti iṣelọpọ. Iwadi ni kutukutu fihan pe resveratrol le ṣe iranlọwọ lati dinku iwuwo ara ati ọra ara ni awọn eniyan ti o ni iṣọn-ara ti iṣelọpọ. Ṣugbọn a nilo iwadi diẹ sii lati jẹrisi.
- Kọ ọra ninu ẹdọ ni awọn eniyan ti o mu diẹ tabi ko si ọti-lile (aisan ẹdọ ti ko ni ọti-lile tabi NAFLD). Ọpọlọpọ iwadii ni kutukutu fihan pe resveratrol ko ṣe ilọsiwaju iṣẹ ẹdọ, ọgbẹ ẹdọ, tabi awọn ipele idaabobo awọ ninu awọn eniyan ti o ni NAFLD.
Ẹri ti ko to lati ṣe iṣiro oṣuwọn fun ...
- Irorẹ. Iwadi ni kutukutu fihan pe lilo gel ti o ni resveratrol si oju fun awọn ọjọ 60 dinku idibajẹ irorẹ.
- Kọ silẹ ni iranti ati awọn ọgbọn ero ti o waye deede pẹlu ọjọ-ori. O jẹ koyewa ti resveratrol ṣe iranlọwọ pẹlu iranti tabi awọn ọgbọn ero ninu awọn eniyan agbalagba. Diẹ ninu iwadii ni kutukutu fihan pe resveratrol le mu awọn ọgbọn ironu ati iranti wa ninu awọn obinrin lẹyin ti ọkunrin ba ti ṣe nkan oṣu. Ṣugbọn iwadi miiran fihan pe resveratrol ti a fun ni awọn abere to ga julọ tabi fun akoko to gun ko ni mu iranti dara sii tabi awọn ọgbọn ero ni awọn agbalagba agbalagba ilera.
- Ẹjẹ ẹjẹ ti o dinku awọn ipele ti amuaradagba ninu ẹjẹ ti a pe ni haemoglobin (beta-thalassaemia). Iwadi ni kutukutu fihan pe gbigbe trans-resveratrol ko mu awọn ipele hemoglobin dara si tabi iwulo fun gbigbe ẹjẹ ni awọn eniyan ti o ni beta-thalassaemia.
- Akàn. Awọn eniyan ti o gba iye ti o ga julọ ti resveratrol ti ounjẹ ko dabi pe o ni eewu kekere ti akàn ni akawe si awọn eniyan ti o jẹ iye kekere.
- Àtọgbẹ. Diẹ ninu awọn iwadii fihan pe resveratrol ṣe ilọsiwaju iṣakoso suga ẹjẹ ninu awọn eniyan ti o ni àtọgbẹ. Ṣugbọn iwadi miiran ko fihan anfani kankan. Resveratrol le ṣe iranlọwọ lati dinku suga ẹjẹ ni awọn alaisan nikan pẹlu awọn ipele suga ẹjẹ ti ko ni iṣakoso daradara. A nilo iwadi diẹ sii lati jẹrisi.
- Ibajẹ Kidirin ninu awọn eniyan ti o ni àtọgbẹ (nephropathy dayabetik). Iwadi ni kutukutu fihan pe gbigba resveratrol pẹlu oogun losartan le mu ilọsiwaju diẹ ninu awọn igbese ti ibajẹ akọn ni awọn eniyan ti o ni nephropathy dayabetik lọ.
- Aarun ẹdọfóró ti o mu ki o nira lati simi (arun onibaje ti o ni idiwọ tabi COPD). Iwadi ni kutukutu daba pe gbigbe ọja apapọ kan ti o ni resveratrol, Vitamin C, zinc, ati flavonoids din diẹ ni ikọ ati iṣelọpọ imukuro ni awọn eniyan ti o ni COPD. Ṣugbọn ko ṣe kedere ti anfaani naa jẹ nitori resveratrol tabi awọn eroja miiran.
- Osteoarthritis. Iwadi ni kutukutu fihan pe fifi resveratrol si awọn itọju deede fun osteoarthritis orokun le mu ilọsiwaju dara, iṣẹ, ati lile diẹ sii ju awọn itọju bošewa nikan lọ.
- Imudarasi ilana iṣoogun ti a pe ni itu ẹjẹ. Iwadi ni kutukutu fihan pe resveratrol le jẹ ki sisẹ ẹjẹ lọ yarayara ni awọn eniyan ti o ni itu ẹjẹ.
- Ẹjẹ homonu ti o fa awọn ẹyin ti o gbooro pẹlu awọn cysts (polycystic ovary syndrome tabi PCOS). Iwadi ni kutukutu fihan pe resveratrol dinku testosterone ninu awọn obinrin pẹlu PCOS. Ṣugbọn kii ṣe ilọsiwaju iwuwo, awọn ipele ọra, irorẹ, tabi idagbasoke irun aifẹ ninu awọn obinrin ti o ni ipo yii.
- Arthritis Rheumatoid (RA). Gbigba resveratrol pẹlu awọn oogun fun RA dabi pe o dinku nọmba ti awọn isẹpo ti o ni irora ati ti o wú. Ṣugbọn a ko mọ boya resveratrol tun ṣe iranlọwọ idinku ibajẹ apapọ.
- Iru arun inu ifun ẹdun (ulcerative colitis). Iwadi ni kutukutu fihan resveratrol le mu awọn aami aisan dara ati dinku iṣẹ ti ọgbẹ ọgbẹ.
- Awọ ti ogbo.
- Kọ silẹ ni iranti ati awọn ọgbọn ero ninu awọn eniyan agbalagba ti o jẹ diẹ sii ju ohun ti o ṣe deede fun ọjọ-ori wọn.
- Ikun ti awọn iṣọn ara (atherosclerosis).
- Iranti ati awọn ọgbọn ero (iṣẹ imọ).
- Awọn ipo miiran.
Resveratrol le faagun awọn ohun elo ẹjẹ ati dinku iṣẹ ti awọn sẹẹli pataki ninu didi ẹjẹ. Diẹ ninu iwadi ṣe imọran pe resveratrol ni awọn estrogen ti ko lagbara (homonu abo). O tun le dinku irora ati wiwu (igbona). Resveratrol le dinku awọn ipele suga (glucose) ninu ẹjẹ ati ṣe iranlọwọ fun ara lati ja lodi si arun. O tun le ṣe idiwọ awọn ọlọjẹ ninu ọpọlọ lati faramọ papọ lati ṣe iranlọwọ lati dena awọn aisan bii aisan Alzheimer.
Nigbati o ba ya nipasẹ ẹnu: Resveratrol jẹ O ṣee ṣe NI Ailewu nigba lilo ninu awọn oye ti a ri ninu awọn ounjẹ. Nigbati o ba ya ni awọn abere to 1500 mg lojoojumọ fun oṣu mẹta, resveratrol jẹ Ailewu Ailewu. Awọn abere to ga julọ ti o to 2000-3000 mg lojoojumọ ti lo lailewu fun awọn oṣu 2-6. Sibẹsibẹ, awọn iwọn lilo giga ti resveratrol ni o seese ki o fa awọn iṣoro ikun.
Nigbati a ba loo si awọ ara: Resveratrol jẹ Ailewu Ailewu nigba lilo si awọ ara fun ọjọ ọgbọn.
Awọn iṣọra pataki & awọn ikilo:
Oyun ati fifun-igbaya: Resveratrol jẹ O ṣee ṣe NI Ailewu nigba lilo ni awọn oye ti a rii ni diẹ ninu awọn ounjẹ. Sibẹsibẹ, lakoko oyun ati fifun-igbaya, orisun ti resveratrol jẹ pataki. A rii Resveratrol ni awọn awọ-ajara, oje eso ajara, ọti-waini, ati awọn orisun ounjẹ miiran. Ko yẹ ki a lo ọti-waini bi orisun ti resveratrol lakoko oyun ati fifun-igbaya.Awọn ọmọde: Resveratrol jẹ Ailewu Ailewu ninu awọn ọmọde nigbati wọn ba fun wọn ni iho imu fun oṣu meji.
Awọn rudurudu ẹjẹ: Resveratrol le fa fifalẹ didi ẹjẹ ati mu eewu ẹjẹ silẹ ni awọn eniyan ti o ni awọn rudurudu ẹjẹ.
Ipo ti o nira fun Hormone bii aarun igbaya, aarun ti ile-ọmọ, akàn ọjẹ, endometriosis, tabi fibroids uterine: Resveratrol le ṣe bi estrogen. Ti o ba ni ipo eyikeyi ti o le jẹ ki o buru sii nipasẹ ifihan si estrogen, maṣe lo resveratrol.
Isẹ abẹ: Resveratrol le mu eewu ẹjẹ pọ si lakoko ati lẹhin iṣẹ abẹ. Da lilo resveratrol o kere ju ọsẹ 2 ṣaaju iṣẹ abẹ ti a ṣeto.
- Dede
- Ṣọra pẹlu apapo yii.
- Awọn oogun ti yipada nipasẹ ẹdọ (Cytochrome P450 1A1 (CYP1A1) awọn iyọti)
- Diẹ ninu awọn oogun ti wa ni iyipada ati fifọ nipasẹ ẹdọ. Resveratrol le dinku bawo ni ẹdọ ṣe fọ diẹ ninu awọn oogun. Ni imọran, gbigba resveratrol pẹlu diẹ ninu awọn oogun ti o fọ nipasẹ ẹdọ le mu awọn ipa ati awọn ipa ẹgbẹ diẹ ninu awọn oogun pọ si.
Diẹ ninu awọn oogun ti o yipada nipasẹ ẹdọ pẹlu chlorzoxazone, theophylline, ati bufuralol. - Awọn oogun ti yipada nipasẹ ẹdọ (Cytochrome P450 1A2 (CYP1A2) sobusitireti)
- Diẹ ninu awọn oogun ti wa ni iyipada ati fifọ nipasẹ ẹdọ. Resveratrol le dinku bawo ni ẹdọ ṣe fọ diẹ ninu awọn oogun. Ni imọran, gbigba resveratrol pẹlu diẹ ninu awọn oogun ti o fọ nipasẹ ẹdọ le mu awọn ipa ati awọn ipa ẹgbẹ diẹ ninu awọn oogun pọ si.
Diẹ ninu awọn oogun ti a yipada nipasẹ ẹdọ pẹlu clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin) prop ), tacrine (Cognex), zileuton (Zyflo), zolmitriptan (Zomig), ati awọn omiiran. - Awọn oogun yipada nipasẹ ẹdọ (Cytochrome P450 1B1 (CYP1B1) sobusitireti)
- Diẹ ninu awọn oogun ti wa ni iyipada ati fifọ nipasẹ ẹdọ. Resveratrol le dinku bawo ni ẹdọ ṣe fọ diẹ ninu awọn oogun. Ni imọran, gbigba resveratrol pẹlu diẹ ninu awọn oogun ti o fọ nipasẹ ẹdọ le mu awọn ipa ati awọn ipa ẹgbẹ diẹ ninu awọn oogun pọ si.
Diẹ ninu awọn oogun ti o yipada nipasẹ ẹdọ pẹlu theophylline, omeprazole, clozapine, progesterone, lansoprazole, flutamide, oxaliplatin, erlotinib, ati caffeine. - Awọn oogun ti a yipada nipasẹ ẹdọ (Cytochrome P450 2C19 (CYP2C19) sobusitireti)
- Diẹ ninu awọn oogun ti wa ni iyipada ati fifọ nipasẹ ẹdọ. Resveratrol le dinku bawo ni ẹdọ ṣe fọ diẹ ninu awọn oogun. Ni imọran, gbigba resveratrol pẹlu diẹ ninu awọn oogun ti o fọ nipasẹ ẹdọ le mu awọn ipa ati awọn ipa ẹgbẹ diẹ ninu awọn oogun pọ si.
Diẹ ninu awọn oogun ti o yipada nipasẹ ẹdọ pẹlu amitriptyline (Elavil), carisoprodol (Soma), citalopram (Celexa), diazepam (Valium), lansoprazole (Prevacid), omeprazole (Prilosec), phenytoin (Dilantin), warfarin, ati ọpọlọpọ awọn miiran. - Awọn oogun yipada nipasẹ ẹdọ (Cytochrome P450 2E1 (CYP2E1) awọn iyọti)
- Diẹ ninu awọn oogun ti wa ni iyipada ati fifọ nipasẹ ẹdọ. Resveratrol le dinku bawo ni ẹdọ ṣe fọ diẹ ninu awọn oogun. Ni imọran, gbigba resveratrol pẹlu diẹ ninu awọn oogun ti o fọ nipasẹ ẹdọ le mu awọn ipa ati awọn ipa ẹgbẹ diẹ ninu awọn oogun pọ si.
Diẹ ninu awọn oogun ti a yipada nipasẹ ẹdọ pẹlu acetaminophen, chlorzoxazone (Parafon Forte), ethanol, theophylline, ati awọn anesthetics bii enflurane (Ethrane), halothane (Fluothane), isoflurane (Forane), methoxyflurane (Penthrane). - Awọn oogun yipada nipasẹ ẹdọ (Cytochrome P450 3A4 (CYP3A4) sobusitireti)
- Diẹ ninu awọn oogun ti wa ni iyipada ati fifọ nipasẹ ẹdọ. Resveratrol le dinku bawo ni ẹdọ ṣe fọ diẹ ninu awọn oogun. Ni imọran, gbigba resveratrol pẹlu diẹ ninu awọn oogun ti o fọ nipasẹ ẹdọ le mu awọn ipa ati awọn ipa ẹgbẹ diẹ ninu awọn oogun pọ si. Sibẹsibẹ, diẹ ninu iwadi akọkọ fihan awọn esi ti o fi ori gbarawọn.
Diẹ ninu awọn oogun ti o yipada nipasẹ ẹdọ pẹlu diẹ ninu awọn oluṣọnwọle ikanni kalisia (diltiazem, nicardipine, verapamil), awọn aṣoju chemotherapeut (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), glucocorticoids, alfentanil (Alfenta) ), fentanyl (Sublimaze), lidocaine (Xylocaine), losartan (Cozaar), fexofenadine (Allegra), midazolam (Ẹsẹ), ati awọn miiran. - Awọn oogun ti o fa fifalẹ didi ẹjẹ (Anticoagulant / Antiplatelet drugs)
- Resveratrol le fa fifalẹ didi ẹjẹ. Gbigba resveratrol pẹlu awọn oogun ti o tun fa fifalẹ didi le mu awọn aye ti ọgbẹ ati ẹjẹ pọ si.
Diẹ ninu awọn oogun ti o fa fifalẹ didi ẹjẹ pẹlu aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, awọn miiran), ibuprofen (Advil, Motrin, awọn miiran), naproxen (Anaprox, Naprosyn, awọn miiran), dalteparin (Fragmin), enoxaparin (Lovenox) , heparin, warfarin (Coumadin), ati awọn omiiran.
- Ewebe ati awọn afikun ti o le fa fifalẹ didi ẹjẹ (Anticoagulant / Antiplatelet herbs and supplements)
- Resveratrol le fa fifalẹ didi ẹjẹ. Lilo rẹ pẹlu awọn ewe miiran tabi awọn afikun ti o le tun fa fifalẹ didi ẹjẹ le mu ki eewu ẹjẹ tabi ọgbẹ pọ si diẹ ninu awọn eniyan. Awọn ewe wọnyi pẹlu angelica, clove, danshen, feverfew, ata ilẹ, Atalẹ, ginkgo, ginseng Panax, chestnut ẹṣin, clover pupa, turmeric, ati awọn omiiran.
- Awọn ọra ati awọn ounjẹ ti o ni ọra ninu
- Gbigba resveratrol pẹlu ounjẹ ti o ga ninu ọra le dinku iye resveratrol ti o gba nipasẹ ara.
AWON AGBA
NIPA ẹnu:
- Fun awọn nkan ti ara korira ti igba (iba iba): Awọn sokiri meji ti sokiri imu ti 0.1% resveratrol sinu imu kọọkan ni igba mẹta / ọjọ fun ọsẹ mẹrin 4.
- Fun isanraju: 500 miligiramu tabi kere si ti resveratrol lojoojumọ fun osu mẹta tabi gun.
Lati kọ diẹ sii nipa bi a ṣe kọ nkan yii, jọwọ wo Awọn Ile-ẹkọ Iṣeduro Alaye Awọn Oogun Adayeba ilana.
- Zhang N, Liang T, Jin Q, Shen C, Zhang Y, Jing P. Iṣu Ṣaina (Dioscorea opposita Thunb.) Mu igbẹ gbuuru ti o ni nkan aporo pọ si, ṣe atunṣe microbiota ti inu, ati mu alekun ipele awọn acids fatty kukuru pọ ninu awọn eku. Ounjẹ Res Int. 2019; 122: 191-198. Wo áljẹbrà.
- Akbari M, Tamtaji OR, Lankarani KB, et al. Awọn ipa ti ifikun resveratrol lori iṣẹ endothelial ati awọn igara ẹjẹ laarin awọn alaisan pẹlu iṣọn-ara ti iṣelọpọ ati awọn rudurudu ti o jọmọ: atunyẹwo eto-ẹrọ ati igbekale apẹẹrẹ ti awọn iwadii ti a sọtọ. Ẹjẹ Titẹ Ẹjẹ Cardiovasc Prev 2019; 26: 305-19. Wo áljẹbrà.
- Köbe T, Witte AV, Schnelle A, et al. Ipa ti resveratrol lori iṣakoso glucose, iṣeto hippocampal ati sisopọ, ati iṣẹ iranti ni awọn alaisan ti o ni aibawọn imọ aitọ. Neurosci iwaju 2017; 11: 105. Wo áljẹbrà.
- Witte AV, Kerti L, Margulies DS, Flöel A. Awọn ipa ti resveratrol lori iṣẹ iranti, asopọ iṣẹ hippocampal, ati iṣelọpọ glucose ni awọn agbalagba ti o ni ilera. J Neurosci 2014; 34: 7862-70. Wo áljẹbrà.
- Mousavi SM, Milajerdi A, Sheikhi A, et al. Atunṣe Resveratrol ṣe pataki ni ipa awọn igbese isanraju: atunyẹwo eto-ẹrọ ati igbekale iwọn-adaṣe onínọmbà ti awọn iwadii iṣakoso ti a sọtọ. Obes Rev 2019; 20: 487-98. Wo áljẹbrà.
- Sattarinezhad A, Roozbeh J, Shirazi Yeganeh B, Omrani GR, Shams M. Resveratrol dinku albuminuria ni nephropathy ti ọgbẹ: aarun idanimọ ibi-iṣakoso afọju afọju meji. Diabetes Metab 2019; 45: 53-9. Wo áljẹbrà.
- Zhang C, Yuan W, Fang J, Wang W, He P, Lei J, Wang C. Imudarasi ti Afikun Resveratrol lodi si Arun Ẹdọ ti kii-Ọti-Ọti: Ayẹwo Meta-ti Awọn idanwo Iṣoogun ti Iṣakoso. PLoS Ọkan. 2016 Oṣu Kẹjọ 25; 11: e0161792. Wo áljẹbrà.
- Poulsen MK, Nellemann B, Bibby BM, et al. Ko si ipa ti resveratrol lori awọn kinetikisi VLDL-TG ati ifamọ insulin ni awọn ọkunrin ti o sanra pẹlu arun ẹdọ ọra ti ko ni ọti-lile. Diabetes Obes Metab. 2018; 20: 2504-2509. Wo áljẹbrà.
- Hussain SA, Marouf BH, Ali ZS, Ahmmad RS. Agbara ati ailewu ti ifowosowopo ti resveratrol pẹlu meloxicam ni awọn alaisan ti o ni osteoarthritis orokun: iwadii ilowosi awakọ kan. Ile-iwosan Interv Aging. 2018; 13: 1621-1630. Wo áljẹbrà.
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