Onkọwe Ọkunrin: Virginia Floyd
ỌJọ Ti ẸDa: 12 OṣU KẹJọ 2021
ỌJọ ImudojuiwọN: 1 OṣU Keje 2024
Anonim
Benefits of Glucosamine
Fidio: Benefits of Glucosamine

Akoonu

Glucosamine jẹ kemikali ti nwaye nipa ti ara ti a rii ninu ara eniyan. O wa ninu omi inu awọn isẹpo. Glucosamine tun wa ni awọn aaye miiran ni iseda. Fun apẹẹrẹ, glucosamine ti a lo ninu awọn afikun awọn ounjẹ ni igbagbogbo gba lati awọn ibon nlanla ti shellfish. Glucosamine tun le ṣe ni yàrá kan.

Awọn ọna oriṣiriṣi oriṣiriṣi ti glucosamine pẹlu imi-ọjọ glucosamine, glucosamine hydrochloride, ati N-acetyl glucosamine. Awọn kemikali oriṣiriṣi wọnyi ni diẹ ninu awọn afijq, ṣugbọn wọn le ma ni awọn ipa kanna nigbati wọn mu bi afikun ijẹẹmu. Pupọ ninu iwadi imọ-jinlẹ lori glucosamine ti ni imi-ọjọ glucosamine.

Diẹ ninu awọn ọja glucosamine ko ni aami ni deede. Ni diẹ ninu awọn ọrọ miiran, iye ti glucosamine niti gidi ninu ọja ti yatọ lati kò si ju 100% ti iye ti a ṣalaye lori aami ọja naa. Diẹ ninu awọn ọja ti ni glucosamine hydrochloride nigbati a ṣe akojọ imi-ọjọ glucosamine lori aami naa.

Imukuro imi-ọjọ Glucosamine ati hydrochloride glucosamine ni a lo julọ fun osteoarthritis. A tun lo Glucosamine fun ọpọlọpọ awọn ipo miiran, ṣugbọn ko si ẹri ijinle sayensi to dara lati ṣe atilẹyin fun awọn lilo wọnyi.

Awọn Ile-ẹkọ Iṣeduro Alaye Awọn Oogun Adayeba awọn oṣuwọn doko da lori ẹri ijinle sayensi ni ibamu si iwọn wọnyi: Imudara, O ṣeeṣe Ki o munadoko, O ṣeeṣe Ki o munadoko, O ṣeeṣe Ki o munadoko, O ṣeeṣe pe ko wulo, ko wulo, ati Ẹri ti ko to lati Oṣuwọn.

Awọn igbelewọn ṣiṣe fun GLUCOSAMINE ni atẹle:


O ṣeeṣe ki o munadoko fun ...

  • Osteoarthritis. Pupọ iwadi fihan pe mu imi-ọjọ glucosamine le pese diẹ ninu iderun irora fun awọn eniyan ti o ni osteoarthritis, paapaa awọn ti o ni osteoarthritis ti awọn kneeskun. Fun diẹ ninu awọn eniyan, imi-ọjọ imi-ọjọ glucosamine le ṣiṣẹ bakanna bi counter-counter ati awọn oogun irora ogun bi acetaminophen tabi ibuprofen. Ṣugbọn awọn oogun irora ṣiṣẹ ni kiakia, lakoko ti imi-ọjọ glucosamine le gba awọn ọsẹ 4-8 ṣaaju ki o to pese iderun irora. Pẹlupẹlu, awọn eniyan ti o mu imi-ọjọ glucosamine nigbagbogbo tun nilo lati mu awọn oogun irora fun awọn igbunaya irora.

    Ọpọlọpọ awọn iru awọn ọja glucosamine lo wa. Iwadi ti o nfihan anfani julọ julọ jẹ fun awọn ọja ti o ni imi-ọjọ glucosamine. Awọn ọja ti o ni glycosamine hydrochloride ko dabi lati ṣiṣẹ bakanna ayafi ti wọn ba mu ni apapo pẹlu awọn eroja miiran. Ọpọlọpọ awọn ọja ni glucosamine pẹlu chondroitin, ṣugbọn ko si ẹri ti o dara pe awọn ọja wọnyi ṣiṣẹ eyikeyi ti o dara julọ ju imi-ọjọ glucosamine lọ nipasẹ ara rẹ.

    Glucosamine imi-ọjọ ko dabi lati ṣe idiwọ awọn eniyan lati ni osteoarthritis.

Ẹri ti ko to lati ṣe iṣiro oṣuwọn fun ...

  • Ibanujẹ apapọ ti o ṣẹlẹ nipasẹ awọn oogun ti a pe ni awọn oludena aromatase (arthralgias ti o ni onidena aromatase). Iwadi ni kutukutu ni imọran pe gbigba apapo ti imi-ọjọ glucosamine ati imi-ọjọ chondroitin ni awọn iwọn meji tabi mẹta ti o pin lojoojumọ fun awọn ọsẹ 24 dinku irora ninu awọn obinrin ti o mu awọn oogun ti o dinku awọn ipele estrogen kekere fun ipele akọkọ ọgbẹ igbaya.
  • Arun okan. Awọn eniyan ti o mu glucosamine le ni eewu kekere ti arun ọkan ninu idagbasoke. Ṣugbọn ko ṣe akiyesi iru iwọn lilo tabi fọọmu ti glucosamine le ṣiṣẹ dara julọ. O tun jẹ koyewa ti eewu kekere yii jẹ lati glucosamine tabi lati tẹle awọn iwa igbesi aye ti ilera.
  • Ibanujẹ. Iwadi ni kutukutu fihan pe gbigbe glucosamine hydrochloride fun awọn ọsẹ 4 le mu awọn aami aiṣan ti ibanujẹ dara si diẹ ninu awọn eniyan ti o ni aibanujẹ.
  • Àtọgbẹ. Awọn eniyan ti o mu glucosamine le ni eewu kekere ti o dagbasoke àtọgbẹ. Ṣugbọn ko ṣe akiyesi iru iwọn lilo tabi fọọmu ti glucosamine le ṣiṣẹ dara julọ. O tun jẹ koyewa ti eewu kekere yii jẹ lati glucosamine tabi lati tẹle awọn iwa igbesi aye ti ilera.
  • Awọn ipele giga ti idaabobo awọ tabi awọn ọra miiran (lipids) ninu ẹjẹ (hyperlipidemia). Iwadi ni kutukutu daba pe glucosamine hydrochloride ko ni ipa idaabobo awọ tabi awọn ipele triglyceride ninu awọn eniyan ti o ni idaabobo awọ giga.
  • Wiwu igba pipẹ (iredodo) ninu apa ijẹẹmu (arun inu ati iredodo tabi IBD). Ẹri ti o wa ni kutukutu wa pe N-acetyl glucosamine ti o ya nipasẹ ẹnu tabi rectally le dinku awọn aami aisan ti IBD ninu awọn ọmọde pẹlu arun Crohn tabi ọgbẹ ọgbẹ.
  • Rudurudu ti o kan awọn egungun ati awọn isẹpo, nigbagbogbo ni awọn eniyan ti o ni aipe selenium (arun Kashin-Beck). Awọn ẹri akọkọ fihan pe gbigba glucosamine hydrochloride pẹlu pẹlu chondroitin imi-ọjọ din irora dinku ati mu ilọsiwaju ara ṣiṣẹ ni awọn agbalagba pẹlu ipo yii. Gbigba glucosamine hydrochloride nikan le ṣiṣẹ bi daradara awọn oogun irora apọju-counter.
  • Orokun orokun. Iwadi ni kutukutu fihan pe gbigba 1500 iwon miligiramu ti imi-ọjọ glucosamine lojoojumọ fun awọn ọjọ 28 ko dinku irora orokun ni awọn elere idaraya ti o tẹle ipalara orokun. Ṣugbọn o dabi pe o mu ilọsiwaju ikunkun dara. Awọn ẹri akọkọ wa pe glucosamine hydrochloride le ṣe iyọda irora fun diẹ ninu awọn eniyan pẹlu irora orokun loorekoore.
  • Ọpọ sclerosis (MS). Iwadi ni kutukutu fihan pe gbigbe imi-ọjọ glucosamine nipasẹ ẹnu lojoojumọ fun awọn oṣu 6 le dinku ifasẹyin ti ọpọlọ-ọpọlọ pupọ.
  • Imularada lẹhin iṣẹ-abẹ. Iwadi ni kutukutu fihan pe mu imi-ọjọ glucosamine ko ni ilọsiwaju iṣẹ, irora, ati iṣẹ ninu awọn elere idaraya ọkunrin ti o ni iṣẹ abẹ lati ṣatunṣe ACL ti o ya. ACL jẹ iṣan ti o mu orokun wa ni ipo lakoko gbigbe.
  • Arthritis Rheumatoid (RA). Iwadi ni kutukutu fihan pe gbigbe glucosamine hydrochloride le dinku irora ṣugbọn kii ṣe nọmba ti o ni fifun ati awọn isẹpo irora.
  • Ọpọlọ. Iwadi ni kutukutu ti ri pe awọn eniyan ti o mu glucosamine le ni eewu kekere diẹ ti nini ikọlu. Ṣugbọn ko ṣe akiyesi iru iwọn lilo tabi fọọmu ti glucosamine le ṣiṣẹ dara julọ. Ṣugbọn ko ṣe akiyesi ti eewu kekere yii ba jẹ lati glucosamine tabi lati awọn iwa igbesi aye ilera.
  • Ẹgbẹ kan ti awọn ipo irora ti o ni ipa lori apapọ bakan ati iṣan (awọn ailera akoko tabi TMD). Iwadi ni kutukutu ko gba boya boya imi-ọjọ glucosamine dinku irora ninu awọn eniyan ti o ni osteoarthritis ti apapọ agbọn.
  • Awọ ti ogbo.
  • Eyin riro.
  • Awọn idagba ti ko ni aarun ni inu ifun nla ati rectum (adenoma colorectal).
  • Iku lati eyikeyi idi.
  • Apapọ apapọ.
  • Aisan àpòòtọ irora (Intystitial cystitis).
  • Iwosan ọgbẹ.
  • Awọn ipo miiran.
A nilo ẹri diẹ sii lati ṣe oṣuwọn imi-ọjọ glucosamine fun awọn lilo wọnyi.

Glucosamine jẹ kẹmika ti a rii ninu ara eniyan. O ti lo nipasẹ ara lati ṣe awọn kemikali miiran ti o ni ipa ninu awọn tendoni ile, awọn isan, kerekere, ati omi sisanra ti o yika awọn isẹpo.

Awọn omi ara ati kerekere ti o yi wọn ka ni a fi awọn isẹpo rọ. Ni diẹ ninu awọn eniyan ti o ni osteoarthritis, kerekere bajẹ ki o di tinrin. Eyi yoo mu abajade ni edekoyede apapọ diẹ, irora, ati lile. Awọn oniwadi ro pe gbigba awọn afikun awọn ohun elo glucosamine le boya mu kerekere ati ito awọn agbegbe ti o wa ni ito pọ tabi ṣe iranlọwọ idiwọ didin awọn nkan wọnyi, tabi boya mejeeji.

Nigbati o ba ya nipasẹ ẹnu: Imi-ọjọ imi-ọjọ Glucosamine jẹ O ṣee ṣe NI Ailewu ni ọpọlọpọ awọn agbalagba. Glucosamine hydrochloride jẹ Ailewu Ailewu fun ọpọlọpọ awọn agbalagba nigbati o ya ni deede fun ọdun meji. N-acetyl glucosamine jẹ tun Ailewu Ailewu nigba ti a mu ni abere ti 3-6 giramu lojoojumọ. Glucosamine le fa diẹ ninu awọn ipa ti o ni irẹlẹ pẹlu ọgbun, inu ọkan, igbuuru, ati àìrígbẹyà. Awọn ipa ẹgbẹ ti ko wọpọ jẹ irọra, awọn aati ara, ati orififo.

Nigbati a ba loo si awọ ara: N-acetyl glucosamine jẹ Ailewu Ailewu nigba lilo fun ọsẹ mẹwa 10.

Nigbati a ba fun ni bi ohun enema (rectally): N-acetyl glucosamine jẹ Ailewu Ailewu nigba lilo ninu awọn abere ti giramu 3-4 lojoojumọ.

Nigbati a fun ni bi ibọn kan: Imi-ọjọ imi-ọjọ Glucosamine jẹ Ailewu Ailewu nigba itasi sinu isan bi ibọn ni ẹẹmeeji ni ọsẹ fun ọsẹ mẹfa.

Awọn iṣọra pataki & awọn ikilo:

Oyun tabi fifun-igbaya: Ko si alaye igbẹkẹle ti o to lati mọ boya imi-ọjọ glucosamine, glucosamine hydrochloride, tabi N-acetyl glucosamine jẹ ailewu lati lo nigbati o loyun tabi fifun-ọmu. Duro ni apa ailewu ki o yago fun lilo.

Ikọ-fèé: Iroyin kan wa ti o sopọ ikọlu ikọ-fèé pẹlu gbigbe glucosamine. A ko mọ daju pe ti o ba jẹ pe glucosamine ni o fa ikọlu ikọ-fèé. Titi di mimọ diẹ sii, awọn eniyan ti o ni ikọ-fèé yẹ ki o ṣọra nipa gbigbe awọn ọja ti o ni glucosamine ninu.

Àtọgbẹ: Diẹ ninu iwadii ni kutukutu daba pe glucosamine le gbe suga ẹjẹ silẹ ni awọn eniyan ti o ni àtọgbẹ. Ṣugbọn iwadi ti o ṣẹṣẹ ṣe ati igbẹkẹle diẹ sii ni bayi fihan pe glucosamine ko dabi pe o ni ipa lori iṣakoso suga ẹjẹ ni awọn eniyan ti o ni iru-ọgbẹ 2. Glucosamine han lati wa ni ailewu fun ọpọlọpọ awọn eniyan ti o ni àtọgbẹ, ṣugbọn o yẹ ki o ṣe abojuto suga ẹjẹ ni pẹkipẹki.

Glaucoma: Glucosamine le mu titẹ inu oju pọ si ati pe o le buru glaucoma. Ti o ba ni glaucoma, sọrọ si olupese iṣẹ ilera rẹ ṣaaju ki o to mu glucosamine.

Idaabobo giga: Diẹ ninu iwadii ni kutukutu daba pe glucosamine le mu awọn ipele idaabobo awọ pọ si. Ṣugbọn iwadii diẹ sii ati igbẹkẹle ti o gbẹkẹle ni bayi fihan pe glucosamine ko dabi lati mu awọn ipele idaabobo awọ pọ si.

Iwọn ẹjẹ giga: Diẹ ninu iwadii ni kutukutu daba pe glucosamine le mu awọn ipele insulini sii. Ṣugbọn iwadii diẹ sii ati igbẹkẹle ti o gbẹkẹle fihan pe glucosamine ko mu titẹ ẹjẹ pọ si. Lati wa ni ẹgbẹ ailewu, ṣe atẹle titẹ ẹjẹ rẹ ni pẹkipẹki ti o ba mu imi-ọjọ glucosamine ati ni titẹ ẹjẹ giga.

Ẹhun Shellfish: Diẹ ninu ibakcdun wa pe awọn ọja glucosamine le fa awọn aati aiṣedede ninu awọn eniyan ti o ni itara si ẹja. A ṣejade Glucosamine lati awọn ẹyin ara ti ede, akan, ati awọn kabu. Awọn aati aiṣedede ninu awọn eniyan ti o ni aleji ẹja shellfish jẹ eyiti o jẹ nipasẹ ẹran ti ẹja shellfish, kii ṣe ikarahun naa. Ṣugbọn diẹ ninu awọn eniyan ti dagbasoke ihuwasi inira lẹhin lilo awọn afikun glucosamine. O ṣee ṣe pe diẹ ninu awọn ọja glucosamine le ni idoti pẹlu apakan ti ẹran eja shellfish ti o le fa ifara inira. Ti o ba ni aleji ara ẹja, ba olupese rẹ sọrọ ṣaaju lilo glucosamine.

Olórí
Maṣe gba apapo yii.
Warfarin (Coumadin)
A lo Warfarin lati fa fifalẹ didi ẹjẹ. Awọn iroyin pupọ lo wa ti o fihan pe mu glucosamine pẹlu tabi laisi chondroitin n mu ipa ti warfarin pọ sii, ṣiṣe didi ẹjẹ paapaa ni aiyara. Eyi le fa ọgbẹ ati ẹjẹ ti o le jẹ pataki. Maṣe gba glucosamine ti o ba n mu warfarin. Ọpọlọpọ awọn oogun abayọ le ṣepọ pẹlu warfarin.
Dede
Ṣọra pẹlu apapo yii.
Awọn oogun fun akàn (Awọn oludena Topoisomerase II)
Diẹ ninu awọn oogun fun iṣẹ aarun nipa dinku bi awọn sẹẹli akàn yara le ṣe daakọ ara wọn. Diẹ ninu awọn onimo ijinlẹ sayensi ro pe glucosamine le ṣe idiwọ awọn oogun wọnyi lati dinku bawo ni awọn sẹẹli tumọ iyara le daakọ ara wọn. Gbigba glucosamine pẹlu diẹ ninu awọn oogun fun akàn le dinku ipa ti awọn oogun wọnyi.

Diẹ ninu awọn oogun ti a lo fun akàn pẹlu etoposide (VP16, VePesid), teniposide (VM26), mitoxantrone, daunorubicin, ati doxorubicin (Adriamycin).
Iyatọ
Ṣọra pẹlu apapo yii.
Acetaminophen (Tylenol, awọn miiran)
Diẹ ninu ibakcdun wa pe gbigba glucosamine SULFATE ati acetaminophen (Tylenol, awọn miiran) papọ le ni ipa bi ọkọọkan ṣe n ṣiṣẹ daradara. Ṣugbọn o nilo alaye diẹ sii lati mọ boya ibaraenisepo yii jẹ aibalẹ nla. Fun bayi, ọpọlọpọ awọn amoye sọ pe o dara lati lo awọn mejeeji papọ.
Awọn oogun fun àtọgbẹ (Awọn oogun Antidiabetes)
Diẹ ninu iwadii ni kutukutu daba pe glucosamine le gbe suga ẹjẹ silẹ ni awọn eniyan ti o ni àtọgbẹ. Ṣugbọn iwadi ti o ṣẹṣẹ ṣe ati igbẹkẹle diẹ sii ni bayi fihan pe glucosamine ko dabi pe o ni ipa lori iṣakoso suga ẹjẹ ni awọn eniyan ti o ni iru-ọgbẹ 2. Nitorinaa, glucosamine jasi ko dabaru pẹlu awọn oogun àtọgbẹ.

Diẹ ninu awọn oogun ti a lo fun àtọgbẹ pẹlu glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Olu) .
Imi-ọjọ Chondroitin
Mu imi-ọjọ chondroitin pẹlu glucosamine HYDROCHLORIDE le dinku awọn ipele ẹjẹ ti glucosamine. Ṣugbọn ko ṣe kedere ti eyi yoo yi awọn ipa ti glucosamine hydrochloride pada.
Ko si awọn ibaraẹnisọrọ ti a mọ pẹlu awọn ounjẹ.
Awọn abere wọnyi ni a ti kẹkọọ ninu iwadi ijinle sayensi:

NIPA ẹnu:
  • Fun osteoarthritis: Glucosamine SULFATE 1500 miligiramu lẹẹkan lojoojumọ tabi 500 miligiramu ni igba mẹta lojumọ, boya nikan tabi papọ pẹlu miligiramu 400 ti imi-ọjọ chondroitin ni igba meji tabi mẹta, ni a ti lo fun ọdun mẹta.
(3R, 4R, 5S, 6R) -3-Amino-6- (Hydroxymethyl) Oxane-2,4,5-Triol Hydrochloride, 2-Amino-2-Deoxy-Glucose, 2-Amino-2-Deoxy-Beta- D-Glucopyranose, 2-Amino-2-Deoxy-D-Glucose Sulfate, Acetylglucosamine, Acétylglucosamine, GlcNAc, 3-Amino-6- (Hydroxymethyl) Oxane-2,4,5-Triol Sulfate, Amino Monosaccharide, Chitostora, Chlor Glucosamina, Chlorhydrate de Glucosamine, Chlorure de Potasiomu-Sulfate de Glucosamine, D-Glucosamine, D-Glucosamine HCl, D-Glucosamine Sulfate, D-Glucosamine Sulphate, G6S, Glucosamine HCl, Glucosamine KCl, Glucosamine N-Acetyl, Sulfate, Sulu-ara Glucosamine 2KCl, Glucosamine Sulfate-Potassium Chloride, Glucosamine Sulphate, Glucosamine Sulphate KCl, Glucosamine-6-Phosphate, GS, Mono-Sulfated Saccharide, N-Acetil Glucosamina, N-Acettyl Glucosamine, N-Acettyl Acétylglucosamine, N-Acetyl D-Glucosamine, N-Acétyl D-Glucosamine, NAG, pGlcNAc, Poly-N-Acetyl Glucosamine, Poly-NAG, Poly- (1-> 3) -N-Acetyl-2-Amino-2- Deoxy-3-ìwọ-Beta-D-Gl ucopyranurosyl-4- (tabi 6-) Sul, p-GlcNAc, Saccharide Mono-Sulfaté, Sulfaté Saccharide, Sulfate de Glucosamine, Sulfate de Glucosamine 2KCl, SG, Sulfated Monosaccharide, Sulfated Saccharide, Sulfato de Glucosamina. 2-Amino-2-Deoxy-D-Glucosehydrochloride, 2-Amino-2-Deoxy-Beta-D-Glucopyranose, 2-Amino-2-Deoxy-Beta-D-Glucopyranose Hydrochloride, Amino Monosaccharide, Chitosamine Hydrochloride, Chlorhidra de , Chlorhydrate de Glucosamine, D-Glucosamine HCl, D-Glucosamine Hydrochloride, Glucosamine, Glucosamine HCl, Glucosamine KCl, Glucosamine-6-Phosphate. 2-Acetamido-2-deoxyglucose, Glucosamine, Glucosamine-6-fosifeti, Glucosamine N-Acetyl, N-Acetil Glucosamina, N-Acétyl Glucosamine, N-Acétyl-Glucosamine, N-Acétylglucosamine, N-Acetyl D-Gluamine, Acétyl D-Glucosamine, NAG, NAG, pGlcNAc, Poly-N-Acetyl Glucosamine, Poly-NAG, p-GlcNAc.

Lati kọ diẹ sii nipa bi a ṣe kọ nkan yii, jọwọ wo Awọn Ile-ẹkọ Iṣeduro Alaye Awọn Oogun Adayeba ilana.


  1. King DE, Xiang J. Glucosamine / Chondroitin ati Iku ni Ẹlẹgbẹ NHAN US kan. J Am Igbimọ Fam Med. 2020; 33: 842-847. Wo áljẹbrà.
  2. Lee DH, Cao C, Zong X, et al. Glucosamine ati Awọn afikun Chondroitin ati Ewu ti Colorectal Adenoma ati Serrated Polyp. Akàn Epidemiol Biomarkers Prev. 2020; 29: 2693-2701. Wo áljẹbrà.
  3. Kumar PNS, Sharma A, Andrade C. Awakọ kan, iwadii aami-ṣiṣi ti ipa ti glucosamine fun itọju ti ibanujẹ nla. Aṣayan Aṣayan Asia J. 2020; 52: 102113. Wo áljẹbrà.
  4. Ma H, Li X, Zhou T, et al. Lilo Glucosamine, iredodo, ati ailagbara jiini, ati iṣẹlẹ ti iru ọgbẹ 2: iwadii ti o nireti ni UK Biobank. Itọju Àtọgbẹ. 2020; 43: 719-25. Wo áljẹbrà.
  5. Bruyere O, Honvo G, Veronese N, et al. Iṣeduro algorithm ti a ṣe imudojuiwọn fun iṣakoso ti osteoarthritis orokun lati European Society for Clinical and As aspect of Osteoporosis, Osteoarthritis, and Musculoskeletal Disease (ESCEO). Semin Arthritis Rheum. 2019 Oṣu kejila; 49: 337-50. Wo áljẹbrà.
  6. Navarro SL, Levy L, Curtis KR, Lampe JW, Hullar MAJ. Awoṣe ti Gut Microbiota nipasẹ Glucosamine ati Chondroitin ni ID kan, Iwadii Pilot Meji-Afọju ninu Awọn eniyan. Awọn oganisimu. 2019 Oṣu kọkanla 23; pii: E610. Wo áljẹbrà.
  7. Restaino TI, Finamore R, Stellavato A, et al. European chondroitin imi-ọjọ ati awọn afikun awọn ounjẹ glucosamine: Didara eto ati igbelewọn opoiye ti a fiwe si awọn oogun. Polym Carbohydr. 2019 Oṣu Kẹwa 15; 222: 114984. Wo áljẹbrà.
  8. Hoban C, Byard R, Musgrave I. Hypersensitive ikolu ti awọn aati oogun si glucosamine ati awọn ipese chondroitin ni Australia laarin 2000 ati 2011. Postgrad Med J. 2019 Oṣu Kẹwa 9. pii: postgradmedj-2019-136957. Wo áljẹbrà.
  9. Kolasinski SL, Neogi T, Hochberg MC, et al. 2019 American College of Rheumatology / Arthritis Foundation itọnisọna fun iṣakoso ti osteoarthritis ti ọwọ, ibadi, ati orokun. Arthritis Rheumatol. 2020 Kínní; 72: 220-33. Wo áljẹbrà.
  10. Tsuruta A, Horiike T, Yoshimura M, Nagaoka I. Igbelewọn ipa ti iṣakoso ti glucosamine ti o ni afikun lori awọn oniṣowo biomarla fun iṣelọpọ kerekere ninu awọn oṣere bọọlu afẹsẹgba: Iwadi iṣakoso ibibo afọju afọju meji. Mol Med Rep.2018 Oṣu Kẹwa; 18: 3941-3948. Epub 2018 Aug 17. Wo áljẹbrà.
  11. Simental-Mendía M, Sánchez-García A, Vilchez-Cavazos F, Acosta-Olivo CA, Peña-Martínez VM, Simental-Mendía LE. Ipa ti glucosamine ati imi-ọjọ chondroitin ni osteoarthritis orokun aami aisan: atunyẹwo eto ati igbekale meta ti awọn idanwo iṣakoso ibibo ti a sọtọ. Rheumatol Int. 2018 Aug; 38: 1413-1428. Epub 2018 Jun 11. Atunwo. Wo áljẹbrà.
  12. Gregori D, Giacovelli G, Minto C, et al. Ẹgbẹ ti Awọn Itọju Ẹkọ nipa Oogun pẹlu Iṣakoso Itọju Igba pipẹ ni Awọn alaisan Pẹlu Knee Osteoarthritis: Atunwo Eto-ọna ati Meta-onínọmbà. JAMA. 2018 Oṣu kejila 25; 320: 2564-2579. Wo áljẹbrà.
  13. Ogata T, Ideno Y, Akai M, et al. Awọn ipa ti glucosamine ni awọn alaisan pẹlu osteoarthritis ti orokun: atunyẹwo eto-ẹrọ ati apẹẹrẹ-onínọmbà. Iwosan Rheumatol. 2018 Oṣu Kẹsan; 37: 2479-2487. Epub 2018 Apr 30. Wo áljẹbrà.
  14. Ma H, Li X, Sun D, ​​ati al. Ijọpọ ti lilo glucosamine ihuwasi pẹlu eewu ti arun inu ọkan ati ẹjẹ: iwadii ti o nireti ni UK Biobank. BMJ. 2019 Oṣu Karun 14; 365: l1628. Wo áljẹbrà.
  15. de Vos BC, Landsmeer MLA, van Middelkoop M, et al. Awọn ipa igba pipẹ ti ilowosi igbesi aye ati glucosamine sulphate roba ni abojuto akọkọ lori orokun iṣẹlẹ OA ninu awọn obinrin apọju. Rheumatology (Oxford). 2017; 56: 1326-1334. Wo áljẹbrà.
  16. Tsuji T, Yoon J, Kitano N, Okura T, Tanaka K. Awọn ipa ti N-acetyl glucosamine ati afikun imi-ọjọ ti chondroitin lori irora orokun ati iṣẹ ikunkun ti ara ẹni royin ni awọn agbalagba agbalagba ati agbalagba ara ilu Japanese: afọju, afọju meji, Iwadii ti iṣakoso ibi-aye. Ogbologbo Clin Exp Res. 2016; 28: 197-205. Wo áljẹbrà.
  17. Runhaar J, Deroisy R, van Middelkoop M, et al. Ipa ti ounjẹ ati idaraya ati ti imi-ọjọ glycosamine ni idena ti osteoarthritis orokun: Awọn abajade siwaju lati Idena orokun Osteoarthritis ni iwadi Awọn obinrin Apọju (PROOF). Semin Arthritis Rheum. 2016 (45 Ipese): S42-8. Wo áljẹbrà.
  18. Roman-Blas JA, Castañeda S, Sánchez-Pernaute O, et al. Itọju Ipọpọ Pẹlu Sulfate Chondroitin ati Awọn Ifihan Sulfate Glucosamine Ko si Didaraju Lori Ibibo fun Idinku ti Iparapọ Apapọ ati Aṣiṣe Iṣẹ-iṣe ni Awọn Alaisan Pẹlu Knee Osteoarthritis: Oniruru-mẹsan-Mefa Oṣupa Kan, Ti a Ṣafihan, Oniduro-Meji, Iwadii Iṣoogun ti Iṣakoso-Iṣakoso. Arthritis Rheumatol. 2017; 69: 77-85. Wo áljẹbrà.
  19. Kongtharvonskul J, Anothaisintawee T, McEvoy M, Attia J, Woratanarat P, Thakkinstian A. Imudara ati aabo ti glucosamine, diacerein, ati awọn NSAID ninu orokun osteoarthritis: atunyẹwo atunyẹwo ati awọn apẹẹrẹ-onínọmbà nẹtiwọọki. Eur J Med Res. 2015; 20:24. Wo áljẹbrà.
  20. Kanzaki N, Ono Y, Shibata H, Moritani T. Afikun ti o ni Glucosamine ṣe ilọsiwaju awọn iṣẹ locomotor ninu awọn akọle pẹlu irora orokun: aifọwọyi, afọju meji, iwadi-iṣakoso ibibo. Ile-iwosan Interv Aging. 2015; 10: 1743-53. Wo áljẹbrà.
  21. Gueniche A, Castiel-Higounenc I. Imudara ti Glucosamine Sulphate ni Agbo Awọ: Awọn abajade lati awoṣe Vivo Anti-Aging ex vivo ati Iwadii Ile-iwosan kan. Awọ Pharmacol Physiol. 2017; 30: 36-41. Wo áljẹbrà.
  22. Eraslan A, Ulkar B. Afikun Glucosamine lẹhin atunkọ iṣọn-ara eegun iwaju ni awọn elere idaraya: iwadii iṣakoso ibibo ti a sọtọ. Res Sports Med. 2015; 23: 14-26. Wo áljẹbrà.
  23. Esfandiari H, Pakravan M, Zakeri Z, et al. Ipa ti glucosamine lori titẹ intraocular: iwadii ile-iwosan ti a sọtọ. Oju. 2017; 31: 389-394.
  24. Murphy RK, Jaccoma EH, Rice RD, Ketzler L. Glucosamine bi Owun to lewu Ewu fun Glaucoma. Ṣe idoko Ophthalmol Vis Sci 2009; 50: 5850.
  25. Eriksen P, Bartels EM, Altman RD, Bliddal H, Juhl C, Christensen R. Ewu ti irẹjẹ ati ami iyasọtọ ṣalaye aiṣedeede ti a ṣe akiyesi ni awọn idanwo lori glucosamine fun iderun aami aisan ti osteoarthritis: igbekale meta ti awọn idanwo iṣakoso ibibo. Itọju Arthritis Res (Hoboken). 2014; 66: 1844-55. Wo áljẹbrà.
  26. Singh JA, Noorbaloochi S, MacDonald R, Maxwell LJ. Chondroitin fun osteoarthritis. Ile-iṣẹ Cochrane Syst Rev. 2015 Jan 28; 1: CD005614. Wo áljẹbrà.
  27. Bruyère O, Cooper C, Pelletier JP, et al. Alaye ifọkanbalẹ kan lori Ilu Yuroopu fun Iṣoogun ati Awọn Ifarahan Iṣowo ti Osteoporosis ati Osteoarthritis (ESCEO) algorithm fun iṣakoso ti osteoarthritis orokun-Lati oogun ti o da lori ẹri si ipo igbesi aye gidi. Semin Arthritis Rheum. 2016; 45 (Ipese 4): S3-11. Wo áljẹbrà.
  28. Kimball AB, Kaczvinsky JR, Li J, et al. Idinku ni hihan hyperpigmentation oju lẹhin lilo ti awọn moisturizers pẹlu apapo ti niacinamide ti oke ati N-acetyl glucosamine: awọn abajade ti aifọwọyi, afọju meji, iwadii iṣakoso ọkọ. Br J Dermatol 2010; 162: 435-41. Wo áljẹbrà.
  29. Madhu K, Chanda K, Saji MJ. Aabo ati ipa ti Curcuma longa jade ni itọju ti orokun ọgbẹ osteoarthritis: idanwo idanimọ ibibo ti a sọtọ. Inflammopharmacology 2013; 21: 129-36. Wo áljẹbrà.
  30. Vetter G. [Itọju ti agbegbe ti awọn arthroses pẹlu awọn glucosamines (Dona 200)]. Munch Med Wochenschr 1969; 111: 1499-502. Wo áljẹbrà.
  31. Setnikar I, Giacchetti C, Zanolo G. Pharmacokinetics ti glucosamine ninu aja ati ninu eniyan. Arzneimittelforschung 1986; 36: 729-35. Wo áljẹbrà.
  32. Basak M, Joseph S, Joshi S, Sawant S. Ifiwera bioavailability ti igbasilẹ akoko ti aramada ati agbekalẹ imi-ọjọ imi-ọjọ glucosamine lulú - iwọn lilo pupọ, ti a sọtọ, ikẹkọ adakoja. Int J Clin Pharmacol Ther 2004; 42: 597-601. Wo áljẹbrà.
  33. Phitak T, Pothacharoen P, Kongtawelert P. Ifiwera awọn ipa itọsẹ glukosi lori ibajẹ kerekere. Ẹjẹ Musculoskelet BMC 2010; 11: 162. Wo áljẹbrà.
  34. Setnikar I, Cereda R, Pacini MA, Revel L. Awọn ohun-ini Antireactive ti imi-ọjọ glucosamine. Arzneimittelforschung 1991; 41: 157-61. Wo áljẹbrà.
  35. Sumantran VN, Chandwaskar R, Joshi AK, Boddul S, Patwardhan B, Chopra A, Wagh UV. Ibasepo laarin chondroprotective ati awọn ipa antiinflammatory ti Withania somnifera root ati glucosamine sulphate lori kerekere osteoarthritic eniyan ni vitro. Agbara Phytother 2008; 22: 1342-8. Wo áljẹbrà.
  36. Setnikar I, Pacini MA, Revel L. Antiarthritic awọn ipa ti imi-ọjọ glucosamine kẹkọọ ni awọn awoṣe ẹranko. Arzneimittelforschung 1991; 41: 542-5. Wo áljẹbrà.
  37. Bassleer C, Henrotin Y, Franchimont P. Imọye-in-vitro ti awọn oogun ti a dabaa bi awọn aṣoju chondroprotective. Int J Tissue React 1992; 14: 231-41. Wo áljẹbrà.
  38. Calamia V, Ruiz-Romero C, Rocha B, Fernández-Puente P, Mateos J, Montell E, Vergés J, Blanco FJ. Iwadi Pharmacoproteomic ti awọn ipa ti chondroitin ati imi-ọjọ glucosamine lori awọn chondrocytes ti ara eniyan. Arthritis Res Ther 2010; 12: R138. Wo áljẹbrà.
  39. AC Graeser AC, Giller K, Wiegand H, Barella L, Boesch Saadatmandi C, Rimbach G. Ipa idapọmọra ti alpha-tocopherol, ascorbic acid, ati selenium bii glucosamine ati chondroitin lori iku sẹẹli ti a fa ati ti idena ti matrix metalloproteinase-3 - awọn ikẹkọ ninu awọn chondrocytes ti aṣa. Awọn eekan. 2009; 15: 27-39. Wo áljẹbrà.
  40. Murphy RK, Ketzler L, Rice RD, Johnson SM, Doss MS, Jaccoma EH. Awọn afikun awọn ohun elo glucosamine ti o gbooro bi oluranlowo hypertensive ocular ṣee ṣe. JAMA Ophthalmol 2013; 131: 955-7. Wo áljẹbrà.
  41. Swinburne LM. Glucosamine sulphate ati osteoarthritis. Lancet 2001; 357: 1617. Wo áljẹbrà.
  42. Akarasereenont P, Chatsiricharoenkul S, Pongnarin P, Sathirakul K, Kongpatanakul S. Bioequivalence iwadi ti 500 mg glucosamine imi-ọjọ ni awọn oluyọọda ilera ti Thai. J Med Assoc Thai 2009; 92: 1234-9. Wo áljẹbrà.
  43. Chopra A, Saluja M, Tillu G, Venugopalan A, Sarmukaddam S, Raut AK, Bichile L, Narsimulu G, Handa R, Patwardhan B. A Imọye Iṣakoso Iwadi Iṣakoso ID ti Awọn ilana Ayurvedic ti o niwọnwọn ni Awọn Ẹkun Osteoarthritis Symptomatic: Ijọba ti India NMITLI Project . Imudara Imudara Imudaniloju Evid Med 2011; 2011: 724291. Wo áljẹbrà.
  44. Wangroongsub Y, Tanavalee A, Wilairatana V, Ngarmukos S. Awọn abajade ile-iwosan ti o jọra laarin glucosamine imi-ọjọ-potasiomu kiloraidi ati glucosamine imi-ọjọ iṣuu kiloraidi ni awọn alaisan pẹlu irẹlẹ ati rirọ orokun osteoarthritis: idanimọ, afọju afọju meji. J Med Assoc Thai 2010; 93: 805-11. Wo áljẹbrà.
  45. Smidt D, Torpet LA, Nauntofte B, Heegaard KM, Pedersen AM. Awọn ajọṣepọ laarin labial ati gbogbo awọn oṣuwọn sisan salivary, awọn aisan eto ati awọn oogun ninu apẹẹrẹ ti awọn eniyan agbalagba. Agbegbe Dent Oral Epidemiol 2010; 38: 422-35. Wo áljẹbrà.
  46. Simon RR, Awọn ami V, Leeds AR, Anderson JW. Atunyẹwo okeerẹ ti lilo glucosamine ẹnu ati awọn ipa lori iṣelọpọ glucose ni awọn eniyan deede ati dayabetik. Diabetes Metab Res Rev 2011; 27: 14-27. Wo áljẹbrà.
  47. Wilkens, P., Scheel, I. B., Grundnes, O., Hellum, C., ati Storheim, K. Ipa ti glucosamine lori ailera ti o ni ibatan ni awọn alaisan ti o ni irora kekere ti o lọra pẹrẹsẹ ati degenerative lumbar osteoarthritis: iwadii iṣakoso ainidii. JAMA 2010; 304: 45-52. Wo áljẹbrà.
  48. Greenlee H, Crew KD, Shao T, Kranwinkel G, Kalinsky K, Maurer M, Brafman L, Insel B, Tsai WY, Hershman DL. Iwadi Ipele II ti glucosamine pẹlu chondroitin lori awọn aami aisan apapọ ti onidalẹkun aromatase ni awọn obinrin ti o ni aarun igbaya ọmu. Ṣe atilẹyin Cancer Itọju 2013; 21: 1077-87. Wo áljẹbrà.
  49. Nieman DC, Shanely RA, Luo B, Dew D, Meaney MP, Sha W. Atunwo ti ijẹẹmu ti iṣowo jẹ ki irora apapọ ni awọn agbalagba agbegbe: afọju meji, iwadii agbegbe ti iṣakoso ibibo. Nutr J 2013; 12: 154. Wo áljẹbrà.
  50. Fransen M, Agaliotis M, Nairn L, Votrubec M, Bridgett L, Su S, Jan S, Oṣu Kẹsan L, Edmonds J, Norton R, Woodward M, Day R; LEGS ṣe iwadi ẹgbẹ ifowosowopo. Glucosamine ati chondroitin fun orokun osteoarthritis: afọju afọju afọju iṣakoso iṣakoso ibi-iṣakoso idanimọ iṣiro ọkan ati awọn ilana idapọ. Ann Rheum Dis 2015; 74: 851-8. Wo áljẹbrà.
  51. Chopra A, Saluja M, Tillu G, Sarmukkaddam S, Venugopalan A, Narsimulu G, Handa R, Sumantran V, Raut A, Bichile L, Joshi K, Patwardhan B. Ayurvedic oogun funni ni yiyan ti o dara si glucosamine ati celecoxib ni itọju ti osteoarthritis aisan orokun: ajẹsara kan, afọju meji, idanwo oogun deede ti iṣakoso. Rheumatology (Oxford) 2013; 52: 1408-17. Wo áljẹbrà.
  52. Levin RM, Krieger NN, ati Winzler RJ. Glucosamine ati ifarada acetylglucosamine ninu eniyan. J Lab Clin Med 1961; 58: 927-932.
  53. Wu H, Liu M, Wang S, Zhao H, Yao W, Feng W, Yan M, Tang Y, Wei M. Ifiwera bioavailability ati awọn ohun-iṣoogun elegbogi ti awọn agbekalẹ 2 ti glucosamine hydrochloride ni awọn oluyọọda agbalagba agbalagba agbalagba Kannada. Arzneimittelforschung. 2012 Aug; 62: 367-71. Wo áljẹbrà.
  54. Liang CM, Tai MC, Chang YH, Chen YH, Chen CL, Chien MW, Chen JT. Glucosamine ṣe idiwọ ifosiwewe idagba epidermal-idagba ilosiwaju ati lilọ kiri-sẹẹli ni awọn sẹẹli epithelial pigment retinal. Mol Vis 2010; 16: 2559-71. Wo áljẹbrà.
  55. Yomogida S, Hua J, Sakamoto K, Nagaoka I. Glucosamine paarẹ iṣelọpọ interleukin-8 ati ikosile ICAM-1 nipasẹ awọn ẹyin HT-29 epithelial epithelial epithelial eniyan ti iṣan ara TNF-alpha. Int J Mol Med 2008; 22: 205-11. Wo áljẹbrà.
  56. Kim CH, Cheong KA, CD Park, Lee AY. Glucosamine ṣe ilọsiwaju atopic dermatitis-bi awọn ọgbẹ awọ ara ni awọn eku NC / Nga nipasẹ didin ti idagbasoke sẹẹli Th2. Scand J Immunol 2011; 73: 536-45. Wo áljẹbrà.
  57. Ju Y, Hua J, Sakamoto K, Ogawa H, Nagaoka I. Glucosamine, amino monosaccharide ti o nwaye nipa ti ara ṣe atunṣe ifilọlẹ sẹẹli endothelial ti o mu ki LL-37 ṣiṣẹ. Int J Mol Med 2008; 22: 657-62. Wo áljẹbrà.
  58. Qiu W, Su Q, Rutledge AC, Zhang J, Adeli K. Glucosamine ti o ni iyọdajẹ endoplasmic reticulum ti o mu ki awọn akopọ B100 apolipoprotein ṣiṣẹ nipasẹ ifihan agbara PERK. J Ikun Resini 2009; 50: 1814-23. Wo áljẹbrà.
  59. Ju Y, Hua J, Sakamoto K, Ogawa H, Nagaoka I. Awoṣe ti ifisilẹ cell endothelial ti o ni ifunni TNF-alpha nipasẹ glucosamine, amino monosaccharide ti o nwaye ni ti ara. Int J Mol Med 2008; 22: 809-15. Wo áljẹbrà.
  60. Ilic MZ, Martinac B, Samiric T, Handley CJ. Awọn ipa ti glucosamine lori pipadanu proteoglycan nipasẹ tendoni, ligament ati awọn aṣa alaye kapusulu apapọ. Cartilage Osteoarthritis 2008; 16: 1501-8. Wo áljẹbrà.
  61. Toegel S, Wu SQ, Piana C, Unger FM, Wirth M, Goldring MB, Gabor F, Viernstein H. Ifiwera laarin awọn ipa chondroprotective ti glucosamine, curcumin, ati diacerein ni IL-1beta-ni iwuri C-28 / I2 chondrocytes. Cartilage Osteoarthritis 2008; 16: 1205-12. Wo áljẹbrà.
  62. Lin YC, Liang YC, Sheu MT, Lin YC, Hsieh MS, Chen TF, Chen CH. Awọn ipa Chondroprotective ti glucosamine ti o ni p38 MAPK ati awọn ipa ọna ami ifihan Akt. Rheumatol Int 2008; 28: 1009-16. Wo áljẹbrà.
  63. Scotto d'Abusco A, Politi L, Giordano C, Scandurra R. Itọsẹ peptidyl-glucosamine yoo kan iṣẹ IKKalpha kinase ninu awọn chondrocytes eniyan. Arthritis Res Ther 2010; 12: R18. Wo áljẹbrà.
  64. Shikhman AR, Brinson DC, Valbracht J, Lotz MK. Awọn ipa ti iṣelọpọ ti iyatọ ti glucosamine ati N-acetylglucosamine ninu awọn chondrocytes ti ara eniyan. Cartilage Osteoarthritis 2009; 17: 1022-8. Wo áljẹbrà.
  65. Uitterlinden EJ, Koevoet JL, Verkoelen CF, Bierma-Zeinstra SM, Jahr H, Weinans H, Verhaar JA, van Osch GJ. Glucosamine mu iṣelọpọ hyaluronic acid pọ si ninu awọn alaye synovium osteoarthritic eniyan. Ẹjẹ Musculoskelet BMC 2008; 9: 120. Wo áljẹbrà.
  66. Hong H, Park YK, Choi MS, Ryu NH, Orin DK, Suh SI, Nam KY, Park GY, Jang BC. Ilana iyatọ si isalẹ ti COX-2 ati MMP-13 ninu awọn awọ ara fibroblasts eniyan nipasẹ glucosamine-hydrochloride. J Dermatol Sci 2009; 56: 43-50. Wo áljẹbrà.
  67. Wu YL, Kou YR, Ou HL, Chien HY, Chuang KH, Liu HH, Lee TS, Tsai CY, Lu ML. Ilana Glucosamine ti iredodo ilaja LPS ni awọn sẹẹli epithelial ti iṣan eniyan. Eur J Pharmacol 2010; 635 (1-3): 219-26. Wo áljẹbrà.
  68. Imagawa K, de Andrés MC, Hashimoto K, Pitt D, Itoi E, Goldring MB, Roach HI, Oreffo RO. Ipa epigenetic ti glucosamine ati ifosiwewe iparun-kappa B (NF-kB) onidena lori awọn chondrocytes eniyan akọkọ - awọn itumọ fun osteoarthritis. Biochem Biophys Res Commun 2011; 405: 362-7. Wo áljẹbrà.
  69. Yomogida S, Kojima Y, Tsutsumi-Ishii Y, Hua J, Sakamoto K, Nagaoka I. Glucosamine, amino monosaccharide ti o nwaye nipa ti ara, npa dextran imi-ọjọ sodium ti o fa idapọ ninu awọn eku. Int J Mol Med 2008; 22: 317-23. Wo áljẹbrà.
  70. Sakai S, Sugawara T, Kishi T, Yanagimoto K, Hirata T. Ipa ti glucosamine ati awọn agbo ogun ti o jọmọ lori degranulation ti awọn sẹẹli masiti ati wiwu wiwu ti dinitrofluorobenzene wa ninu awọn eku. Igbesi aye Sci 2010; 86 (9-10): 337-43. Wo áljẹbrà.
  71. Hwang MS, Baek WK. Glucosamine n fa iku sẹẹli autophagic nipasẹ iwuri ti wahala ER ninu awọn sẹẹli akàn glioma eniyan. Biochem Biophys Res Commun 2010; 399: 111-6. Wo áljẹbrà.
  72. Park JY, Park JW, Suh SI, Baek WK. D-glucosamine isalẹ-ṣe atunṣe HIF-1alpha nipasẹ didin ti itumọ amuaradagba ninu awọn sẹẹli akàn DU145. Biochem Biophys Res Commun 2009; 382: 96-101. Wo áljẹbrà.
  73. Chesnokov V, Sun C, Itakura K. Glucosamine npa fifa soke ti iṣan carcinoma prostate eniyan Awọn ẹyin DU145 nipasẹ didena ifihan agbara STAT3. Ẹjẹ Akàn Int 2009; 9: 25. Wo áljẹbrà.
  74. Tsai CY, Lee TS, Kou YR, Wu YL. Glucosamine dẹkun iṣelọpọ IL-1beta ti o ni ilaja ti iṣelọpọ IL-8 ninu awọn sẹẹli akàn pirositeti nipasẹ idinku MAPK. J Ẹrọ Biochem 2009; 108: 489-98. Wo áljẹbrà.
  75. Kim DS, Park KS, Jeong KC, Lee BI, Lee CH, Kim SY. Glucosamine jẹ onitumọ chemo-sensitizer ti o munadoko nipasẹ ihamọ 2 transglutaminase. Iwe akàn 2009; 273: 243-9. Wo áljẹbrà.
  76. Naito K, Watari T, Furuhata A, Yomogida S, Sakamoto K, Kurosawa H, Kaneko K, Nagaoka I. Igbelewọn ti ipa ti glucosamine lori apẹẹrẹ ekuro osteoarthritis. Igbesi aye Sci 2010; 86 (13-14): 538-43. Wo áljẹbrà.
  77. Weiden S ati Igi IJ. Awọn ayanmọ ti glucosamine hydrochloride itasi iṣan sinu eniyan. J Pathol Pathol 1958; 11: 343-349.
  78. Satia JA, Littman A, Slatore CG, Galanko JA, White E. Awọn ajọṣepọ ti egboigi ati awọn afikun pataki pẹlu ẹdọfóró ati eewu akàn awọ ninu ẹkọ VITamins ati Igbesi aye. Akàn Epidemiol Biomarkers Prev 2009; 18: 1419-28. Wo áljẹbrà.
  79. Audimoolam VK, Bhandari S. Nephritis interstitial nephritis ti a fa nipasẹ glucosamine. Nephrol Dial Transplant 2006; 21: 2031. Wo áljẹbrà.
  80. Ossendza RA, Grandval P, Chinoune F, Rocher F, Chapel F, Bernardini D. [Aarun jedojedo cholestatic ti o lagbara nitori glucosamine forte] Gastroenterol Iwosan Biol. 2007 Oṣu Kẹwa; 31: 449-50. Wo áljẹbrà.
  81. Wu D, Huang Y, Gu Y, Fan W. Awọn ipa ti awọn ipalemo oriṣiriṣi ti glucosamine fun itọju ti osteoarthritis: igbekale meta ti aifọwọyi, afọju meji, awọn idanwo iṣakoso ibibo. Int J Ilera iṣe 2013; 67: 585-94. Wo áljẹbrà.
  82. Provenza JR, Shinjo SK, Silva JM, Peron CR, Rocha FA. Apapo glucosamine ati imi-ọjọ chondroitin, lẹẹkan tabi ni igba mẹta lojoojumọ, n pese analgesia ti o baamu nipa iṣoogun ni orokun osteoarthritis. Clin Rheumatol 2015; 34: 1455-62. Wo abọ-ọrọ.
  83. Kwoh CK, Roemer FW, Hannon MJ, Moore CE, Jakicic JM, Guermazi A, Green SM, Evans RW, Boudreau R. Ipa ti glucosamine ẹnu lori ipilẹ apapọ ninu awọn ẹni-kọọkan pẹlu irora orokun onibaje: idanimọ kan, iṣakoso iwadii ti iṣakoso ibibo. Arthritis Rheumatol. Oṣu Kẹwa 2014; 66: 930-9. Wo áljẹbrà.
  84. von Felden J, Montani M, Kessebohm K, Stickel F. Ipalara ẹdọ nla ti o fa oogun ti o farawe jedojedo autoimmune lẹhin gbigbe ti awọn afikun awọn ounjẹ ti o ni glucosamine ati imi-ọjọ chondroitin. Int J Clin Pharmacol Ther 2013; 51: 219-23. Wo áljẹbrà.
  85. Hochberg MC, Martel-Pelletier J, Monfort J, Möller I, Castillo JR, Arden N, Berenbaum F, Blanco FJ, Conaghan PG, Doménech G, Henrotin Y, Pap T, Richette P, Sawitzke A, du Souich P, Pelletier JP ; ni orukọ Ẹgbẹ Iwadi MOVES. Apapo chondroitin imi-ọjọ ati glucosamine fun orokun irora osteoarthritis: ọpọ-ọpọlọ, ti a sọtọ, afọju meji, iwadii ti kii ṣe alaini dipo celecoxib. Ann Rheum Dis 2016; 75: 37-44. Wo áljẹbrà.
  86. Cerda C, Bruguera M, Parés A. Hepatotoxicity ti o ni nkan ṣe pẹlu glucosamine ati imi-ọjọ chondroitin ni awọn alaisan ti o ni arun ẹdọ onibaje. World J Gastroenterol 2013; 19: 5381-4. Wo áljẹbrà.
  87. Fox BA, Stephens MM. Glucosamine hydrochloride fun itọju awọn aami aisan osteoarthritis. Ile-iwosan Interv Aging 2007; 2: 599-604. Wo áljẹbrà.
  88. Vlad, S. C., LaValley, M. P., McAlindon, T. E., ati Felson, D. T. Glucosamine fun irora ni osteoarthritis: kilode ti awọn abajade iwadii yatọ? Arthritis Rheum 2007; 56: 2267-2277. Wo áljẹbrà.
  89. Reginster, J. Y. Ipa ti imi-ọjọ imi-ọjọ glucosamine ni osteoarthritis: ija owo ati aiṣe-aje ti iwulo. Arthritis Rheum 2007; 56: 2105-2110. Wo áljẹbrà.
  90. Frestedt, J. L., Walsh, M., Kuskowski, M. A., ati Zenk, J. L. Afikun nkan ti o wa ni erupe ile n pese iderun lati awọn aami aiṣan osteoarthritis: iwadii awakọ awakọ alaimọ kan. Nutr J 2008; 7: 9. Wo áljẹbrà.
  91. Yue, J., Yang, M., Yi, S., Dong, B., Li, W., Yang, Z., Lu, J., Zhang, R., ati Yong, J. Chondroitin imi-ọjọ ati / tabi glucosamine hydrochloride fun arun Kashin-Beck: iṣupọ iṣupọ kan, iwadi iṣakoso ibibo. Osteoarthritis. Cartilage. 2012; 20: 622-629. Wo áljẹbrà.
  92. Kanzaki, N., Saito, K., Maeda, A., Kitagawa, Y., Kiso, Y., Watanabe, K., Tomonaga, A., Nagaoka, I., ati Yamaguchi, H. Ipa ti afikun ijẹẹmu ti o ni glucosamine hydrochloride, imi-ọjọ chondroitin ati quercetin glycosides lori osteoarthritis orokun aami aisan: aifọwọyi kan, afọju meji, iwadi-iṣakoso ibibo. J.Sci. Ounjẹ Ogbin. 3-15-2012; 92: 862-869. Wo áljẹbrà.
  93. Wandel, S., Juni, P., Tendal, B., Nuesch, E., Villiger, PM, Welton, NJ, Reichenbach, S., ati Trelle, S. Awọn ipa ti glucosamine, chondroitin, tabi pilasibo ni awọn alaisan pẹlu osteoarthritis ti ibadi tabi orokun: onínọmbà meta. BMJ 2010; 341: c4675. Wo áljẹbrà.
  94. Sawitzke, AD, Shi, H., Finco, MF, Dunlop, DD, Harris, CL, Singer, NG, Bradley, JD, Silver, D., Jackson, CG, Lane, NE, Oddis, CV, Wolfe, F. , Lisse, J., Furst, DE, Bingham, CO, Reda, DJ, Moskowitz, RW, Williams, HJ, ati Clegg, DO Isẹgun iwosan ati aabo ti glucosamine, chondroitin sulphate, apapọ wọn, celecoxib tabi pilasibo ti a mu lati ṣe itọju osteoarthritis ti orokun: Awọn abajade ọdun 2 lati GAIT. Ann.Rheum.Dis. 2010; 69: 1459-1464. Wo áljẹbrà.
  95. Jackson, CG, Plaas, AH, Sandy, JD, Hua, C., Kim-Rolands, S., Barnhill, JG, Harris, CL, ati Clegg, DO Awọn oogun elegbogi eniyan ti ifun ẹnu ti glucosamine ati imi-ọjọ chondroitin mu lọtọ tabi ni apapo. Ẹrọ kerekere ti Osteoarthritis 2010; 18: 297-302. Wo áljẹbrà.
  96. Lee, Y. H., Woo, J. H., Choi, S. J., Ji, J. D., ati Song, G. G. Ipa ti glucosamine tabi imi-ọjọ chondroitin lori ilọsiwaju osteoarthritis: apẹẹrẹ-onínọmbà. Rheumatol Int 2010; 30: 357-363. Wo áljẹbrà.
  97. Theoharides, T. C., Kempuraj, D., Vakali, S., ati Sant, G. R. Itoju ti cystitis interstitial / iṣọn-aisan aporo ti o ni irora pẹlu CystoProtek - afikun afikun ohun alumọni ti ara. Ṣe J Urol 2008; 15: 4410-4414. Wo áljẹbrà.
  98. Dudics, V., Kunstar, A., Kovacs, J., Lakatos, T., Geher, P., Gomor, B., Monostori, E., ati Uher, F. Chondrogenic agbara ti awọn sẹẹli ẹyin mesenchymal lati awọn alaisan ti o ni rheumatoid arthritis ati osteoarthritis: awọn wiwọn ninu eto microculture. Awọn ara Ẹyin. Awọn ara ilu 2009; 189: 307-316. Wo áljẹbrà.
  99. Cahlin, B. J. ati Dahlstrom, L. Ko si ipa ti imi-ọjọ glucosamine lori osteoarthritis ninu awọn isẹpo igba-akoko - ẹkọ alailẹgbẹ, iṣakoso, iwadi igba diẹ. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 112: 760-766. Wo áljẹbrà.
  100. Shaygannejad, V., Janghorbani, M., Savoj, M. R., ati Ashtari, F. Awọn ipa ti imi-ọjọ glucosamine imi-ọjọ lori ifasẹyin-fifiranṣẹ ilọsiwaju sclerosis pupọ: awọn awari akọkọ ti aifọwọyi, iwadii iṣakoso ibibo. Neurol Res 2010; 32: 981-985. Wo áljẹbrà.
  101. Ostojic, S. M., Arsic, M., Prodanovic, S., Vukovic, J., ati Zlatanovic, M. Glucosamine iṣakoso ninu awọn elere idaraya: awọn ipa lori imularada ti ipalara ikun nla. Awọn ere idaraya Res 2007; 15: 113-124. Wo áljẹbrà.
  102. Rozendaal, RM, Uitterlinden, EJ, van Osch, GJ, Garling, EH, Willemsen, SP, Ginai, AZ, Verhaar, JA, Weinans, H., Koes, BW, ati Bierma-Zeinstra, SM Ipa ti glucosamine sulphate lori apapọ Idinku aaye, irora ati iṣẹ ni awọn alaisan ti o ni osteoarthritis hip; awọn itupalẹ ẹgbẹ-ẹgbẹ ti iwadii iṣakoso ti a sọtọ. Ẹrọ kerekere ti Osteoarthritis 2009; 17: 427-432. Wo áljẹbrà.
  103. Marti-Bonmati, L., Sanz-Requena, R., Rodrigo, J. L., Alberich-Bayarri, A., ati Carot, J. M. Glucosamine imi-ọjọ imi-ọjọ lori kerekere patellar degenerated: awọn awari akọkọ nipasẹ awoṣe awoṣe resonance magnetic pharmacokinetic. Eur Radiol 2009; 19: 1512-1518. Wo áljẹbrà.
  104. Rovati LC, Giacovelli G, Annefeld N, ati et al. Iwadi nla kan, ti a ti sọtọ, iṣakoso ibibo, afọju afọju ti imi-ọjọ glucosamine vs piroxocam ati lapapo wọn lori awọn kinetikisi ti ipa aami aisan ni osteoarthritis orokun. Cartilage Osteoarth 1994; 2 (pese 1): 56.
  105. Nandhakumar J. Agbara, ifarada, ati aabo ti antiinflammatory multicomponent pẹlu glucosamine hydrochloride vs glucosamine imi-ọjọ la NSAID kan ni itọju ti osteoarthritis orokun - ti a sọtọ, ti ifojusọna, afọju meji, iwadii afiwera. Ile-iṣẹ Integr Med J 2009; 8: 32-38.
  106. Muller-Fassbender, H., Bach, G. L., Haase, W., Rovati, L. C., ati Setnikar, I. Glucosamine imi-ọjọ ti a fiwe si ibuprofen ni osteoarthritis ti orokun. Ẹrọ kerekere ti Osteoarthritis 1994; 2: 61-69. Wo áljẹbrà.
  107. Towheed, T. E. ati Anastassiades, T. P. Glucosamine itọju ailera fun osteoarthritis. J Rheumatol 1999; 26: 2294-2297. Wo áljẹbrà.
  108. Zhang, W., Nuki, G., Moskowitz, RW, Abramson, S., Altman, RD, Arden, NK, Bierma-Zeinstra, S., Brandt, KD, Croft, P., Doherty, M., Dougados, M., Hochberg, M., Hunter, DJ, Kwoh, K., Lohmander, LS, ati Tugwell, awọn iṣeduro P. OARSI fun iṣakoso ti hip ati orokun osteoarthritis: apakan III: Awọn ayipada ninu ẹri ti o tẹle imudara imularada eleto ti iwadi ti a tẹ nipasẹ Oṣu Kini Ọdun 2009. Osteoarthritis Cartilage 2010; 18: 476-499. Wo áljẹbrà.
  109. Petersen, SG, Beyer, N., Hansen, M., Holm, L., Aagaard, P., Mackey, AL, ati Kjaer, M. Nonsteroidal egboogi-iredodo tabi glucosamine dinku irora ati ilọsiwaju agbara iṣan pẹlu ikẹkọ ikẹkọ ni idanwo idanimọ ti a sọtọ ti awọn alaisan osteoarthritis orokun. Arch Phys Med Atunṣe 2011; 92: 1185-1193. Wo áljẹbrà.
  110. Noack, W., Fischer, M., Forster, K. K., Rovati, L. C., ati Setnikar, I. Glucosamine imi-ọjọ ni osteoarthritis ti orokun. Ẹrọ kekere ti Osteoarthritis 1994; 2: 51-59. Wo áljẹbrà.
  111. Giordano N, Fioravanti A, Papakostas P, et al. Igbara ati ifarada ti imi-ọjọ glucosamine ni itọju ti osteoarthritis orokun: aifọwọyi kan, afọju meji, iwadii iṣakoso ibibo. Ile-iṣẹ Ile-iṣẹ Curr Ther Exp 2009; 70: 185-196. Wo áljẹbrà.
  112. Yamamoto, T., Kukuminato, Y., Nui, I., Takada, R., Hirao, M., Kamimura, M., Saitou, H., Asakura, K., ati Kataura, A. [Ibasepo laarin eruku adodo birch aleji ati ifunra ti pharyngeal si eso]. Nippon Jibiinkoka Gakkai Kaiho 1995; 98: 1086-1091. Wo áljẹbrà.
  113. Kawasaki T, Kurosawa H, Ikeda H, et al. Awọn ipa afikun ti glucosamine tabi risedronate fun itọju ti osteoarthritis ti orokun ni idapo pẹlu adaṣe ile: iwadii ti a sọtọ ti oṣu-18. J Egungun Miner Metab 2008; 26: 279-87. Wo áljẹbrà.
  114. Nelson BA, Robinson KA, Buse MG. Glukosi giga ati glucosamine n mu ki itọju insulini nipasẹ awọn ilana oriṣiriṣi wa ni adipocytes 3T3-L1. Àtọgbẹ 2000; 49: 981-91. Wo áljẹbrà.
  115. Baron AD, Zhu JS, Zhu JH, et al. Glucosamine n mu ki itọju insulini wa ni vivo nipa nini ipa gbigbe GLUT 4 ninu iṣan ara. Awọn ilọsiwaju fun majele ti glucose. J Ile-iwosan Nawo 1995; 96: 2792-801. Wo áljẹbrà.
  116. Eggertsen R, Andreasson A, Andren L. Ko si awọn ayipada ti awọn ipele idaabobo awọ pẹlu ọja glucosamine ti o wa ni iṣowo ni awọn alaisan ti a tọju pẹlu awọn oogun kekere ti ora: iṣakoso kan, ti a sọtọ, ṣiṣi agbelebu-lori. BMCPharmacol Toxicol 2012; 13: 10. Wo áljẹbrà.
  117. Liu W, Liu G, Pei F, et al. Aisan Kashin-Beck ni Sichuan, China: ijabọ ti awakọ kan ṣii idanwo itọju. J Ile-iwosan Rheumatol 2012; 18: 8-14. Wo áljẹbrà.
  118. Nakamura H, Masuko K, Yudoh K, et al. Awọn ipa ti iṣakoso glucosamine lori awọn alaisan pẹlu arthritis rheumatoid. Rheumatol Int 2007; 27: 213-8. Wo áljẹbrà.
  119. Bruyere O, Pavelka K, Rovati LC, et al. Apapọ rirọpo apapọ lẹhin itọju glycosamine sulphate ni orokun osteoarthritis: awọn abajade ti akiyesi ọdun mẹjọ 8 ti awọn alaisan lati ọdun mẹta mẹta ti tẹlẹ, ti a sọtọ, awọn iwadii iṣakoso ibibo. Ẹrọ kerekere ti Osteoarthritis 2008; 16: 254-60. Wo áljẹbrà.
  120. Bijlsma JWJ, Lafeber FPJG. Imi-ọjọ Glucosamine ni osteoarthritis: Igbimọ imulẹ tun wa. Ann Intern Med 2008; 148: 315-6. Wo áljẹbrà.
  121. Rozendaal RM, Koes BW, van Osch GJVM, et al. Ipa ti imi-ọjọ glucosamine lori ibadi osteoarthritis: Iwadii ti a sọtọ. Ann Intern Med 2008; 148: 268-77. Wo áljẹbrà.
  122. Persiani S, Rotini R, Trisolino G, et al. Awọn ifọkansi synovial ati pilasima glucosamine ni awọn alaisan osteoarthritic ti o tẹle kristali ọlọ glycosamine sulphate ni iwọn itọju. Ẹrọ kekere ti Osteoarthritis 2007; 15: 764-72. Wo áljẹbrà.
  123. Yue QY, Strandell J, Myrberg O. Lilo ilopọ ti glucosamine le ni ipa ipa ti warfarin. Ile-iṣẹ Abojuto Uppsala. Wa ni: www.who-umc.org/graphics/9722.pdf (Wọle si 28 Kẹrin 2008).
  124. Knudsen J, Sokol GH. Ibarapọ glucosamine-warfarin ti o lagbara ti o mu ki ipin apapọ ti kariaye pọ si: ijabọ ọran ati atunyẹwo ti awọn iwe ati ibi ipamọ data MedWatch. Ile-iwosan Pharmacotherapy 2008; 28: 540-8. Wo áljẹbrà.
  125. Muniyappa R, Karne RJ, Hall G, et al. Glycosamine ti ẹnu fun awọn ọsẹ 6 ni awọn abere to ṣe deede ko fa tabi buru si itọju insulini tabi aiṣedeede endothelial ni titẹ si apakan tabi awọn akọle ti o sanra. Àtọgbẹ 2006; 55: 3142-50. Wo áljẹbrà.
  126. Tannock LR, Kirk EA, King VL, et al. Afikun Glucosamine yara ni kutukutu ṣugbọn kii ṣe pẹ atherosclerosis ni awọn eku alaini olugba LDL. J Nutr 2006; 136: 2856-61. Wo áljẹbrà.
  127. Pham T, Cornea A, Blick KE, et al. Glycosamine ti ẹnu ni awọn abere ti a lo lati tọju osteoarthritis buru si itọju insulini. Am J Med Sci 2007; 333: 333-9. Wo áljẹbrà.
  128. Messier SP, Mihalko S, Loeser RF, ati al. Glucosamine / chondroitin ni idapo pẹlu adaṣe fun itọju ti osteoarthritis orokun: iwadi iṣaaju. Ẹrọ kekere ti Osteoarthritis 2007; 15: 1256-66. Wo áljẹbrà.
  129. Jump JL, Lin SW. Ipa ti glucosamine lori iṣakoso glucose. Ann Pharmacother 2006; 40: 694-8. Wo áljẹbrà.
  130. Bush TM, Rayburn KS, Holloway SW, et al.Awọn ibaraẹnisọrọ odi laarin egboigi ati awọn nkan ti o jẹun ati awọn oogun oogun: iwadii ile-iwosan kan. Omiiran Ilera Med 2007; 13: 30-5. Wo áljẹbrà.
  131. Towheed TE, Maxwell L, Anastassiades TP, et al. Itọju ailera Glucosamine fun atọju osteoarthritis. Ile-iṣẹ Cochrane Syst Rev 2005;: CD002946. Wo áljẹbrà.
  132. Poolsup N, Suthisisang C, Channark P, Kittikulsuth W. Glucosamine itọju igba pipẹ ati lilọsiwaju ti orokun osteoarthritis: atunyẹwo eto-ẹrọ ti awọn idanwo idanimọ alaimọ. Ann Pharmacother 2005; 39: 1080-7. Wo áljẹbrà.
  133. Qiu GX, Weng XS, Zhang K, et al. [Aarin pupọ, ti a sọtọ, idanwo itọju ti iṣakoso ti glucosamine hydrochloride / imi-ọjọ ni itọju ti orokun osteoarthritis]. Zhonghua Yi Xue Za Zhi 2005; 85: 3067-70. Wo áljẹbrà.
  134. Clegg DO, Reda DJ, Harris CL, et al. Glucosamine, imi-ọjọ chondroitin, ati awọn meji ni apapọ fun irora orokun osteoarthritis. N Engl J Med 2006; 354: 795-808. Wo áljẹbrà.
  135. Herrero-Beaumont G, Ivorra JA, Del Carmen Trabado M, et al. Imu imi-ọjọ Glucosamine ni itọju awọn aami aiṣan osteoarthritis orokun: aifọwọyi kan, afọju meji, iwadi iṣakoso ibi-aye nipa lilo acetaminophen bi olufiwe ẹgbẹ kan. Arthritis Rheum 2007; 56: 555-67. Wo áljẹbrà.
  136. Theodosakis J. Afọju ti a sọtọ, afọju meji, iwadii iṣakoso ibibo ti ipara ti agbegbe ti o ni imi-ọjọ glucosamine, imi-ọjọ chondroitin, ati kafufo fun osteoarthritis ti orokun. J Rheumatol 2004; 31: 826. Wo áljẹbrà.
  137. Zhang W, Doherty M, Arden N, et al. Awọn iṣeduro ti o da lori ẹri EULAR fun iṣakoso ti osteoarthritis ibadi: ijabọ ti agbara iṣẹ-ṣiṣe ti EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 2005; 64: 669-81. Wo áljẹbrà.
  138. Towheed TE, Anastassiades TP, Shea B, et al. Itọju ailera Glucosamine fun atọju osteoarthritis. Ile-iṣẹ Cochrane Syst Rev 2001; 1: CD002946. Wo áljẹbrà.
  139. McAlindon T. Kini idi ti awọn iwadii ile-iwosan ti glucosamine ko ṣe ni iṣọkan iṣọkan? Ile-iwosan Rheum Dis North Am 2003; 29: 789-801. Wo áljẹbrà.
  140. Cibere J, Kopec JA, Thorne A, et al. Aileto, afọju meji, iwadii idaduro glucosamine iṣakoso ibi-iṣakoso ni osteoarthritis orokun. Arthritis Rheum 2004; 51: 738-45. Wo áljẹbrà.
  141. McAlindon T, Formica M, LaValley M, et al. Imudara ti glucosamine fun awọn aami aiṣan ti osteoarthritis orokun: awọn abajade lati orisun idanimọ iṣakoso afọju meji afọju ti o da lori intanẹẹti. Am J Med 2004; 117: 643-9. Wo áljẹbrà.
  142. Bruyere O, Pavelka K, Rovati LC, et al. Imukuro imi-ọjọ Glucosamine dinku ilọsiwaju osteoarthritis ninu awọn obinrin postmenopausal pẹlu orokun osteoarthritis: ẹri lati awọn ẹkọ ọdun mẹta meji. Menopause 2004; 11: 138-43. Wo áljẹbrà.
  143. Grey HC, Hutcheson PS, Slavin RG. Njẹ ailewu glucosamine ni awọn alaisan ti o ni aleji ti ẹja (lẹta)? J Allergy Clin Immunol 2004; 114: 459-60. Wo áljẹbrà.
  144. Tannis AJ, Barban J, Ṣẹgun JA. Ipa ti afikun glucosamine lori aawẹ ati aisi-pilasima pilasima ti ko ni iwẹ ati awọn ifọkansi isulini ara inu awọn eniyan alara. Cartilage Osteoarthritis 2004; 12: 506-11. Wo áljẹbrà.
  145. Weimann G, Lubenow N, Selleng K, et al. Imi imi-ọjọ Glucosamine ko ni ṣe agbekọja pẹlu awọn egboogi ti awọn alaisan pẹlu thrombocytopenia ti a fa sinu heparin. Eur J Haematol 2001; 66: 195-9. Wo áljẹbrà.
  146. Hughes R, Carr A. Aṣoju, afọju meji, idanwo iṣakoso ibibo ti glucosamine sulphate gẹgẹbi itupalẹ ninu osteoarthritis ti orokun. Rheumatology (Oxford) 2002; 41: 279-84. . Wo áljẹbrà.
  147. Rozenfeld V, Crain JL, Callahan AK. Imudara ti o ṣeeṣe ti ipa warfarin nipasẹ glucosamine-chondroitin. Am J Ilera Syst Pharm 2004; 61: 306-307. Wo áljẹbrà.
  148. Towheed TE. Ipo lọwọlọwọ ti itọju glucosamine ni osteoarthritis. Arthritis Rheum 2003; 49: 601-4. Wo áljẹbrà.
  149. Guillaume MP, Peretz A. Isopọ to ṣeeṣe laarin itọju glucosamine ati majele kidirin: asọye lori lẹta nipasẹ Danao-Camara. Arthritis Rheum 2001; 44: 2943-4. Wo áljẹbrà.
  150. Danao-Camara T. Awọn ipa ẹgbẹ ti o lagbara ti itọju pẹlu glucosamine ati chondroitin. Arthritis Rheum 2000; 43: 2853. Wo áljẹbrà.
  151. Cohen M, Wolfe R, Mai T, Lewis D. A ti sọtọ, afọju meji, ayewo iṣakoso ibibo ti ọra-wara ti o ni imi-ọjọ glycosamine, imi-ọjọ chondroitin, ati kafufo fun osteoarthritis ti orokun. J Rheumatol 2003; 30: 523-8 .. Wo áljẹbrà.
  152. Yu JG, Boies SM, Olefsky JM. Ipa ti imi-ọjọ imi-ọjọ glucosamine lori ifamọ insulini ninu awọn eniyan. Itọju Àtọgbẹ 2003; 26: 1941-2. Wo áljẹbrà.
  153. Setnikar I, Rovati LC. Gbigba, pinpin, iṣelọpọ ati iyọkuro ti imi-ọjọ glucosamine. Atunwo kan. Arzneimittelforschung 2001; 51: 699-725. Wo áljẹbrà.
  154. Hoffer LJ, Kaplan LN, Hamadeh MJ, et al. Sulfate le ṣe ilaja ipa itọju ti imi-ọjọ glucosamine. Iṣelọpọ 2001; 50: 767-70 .. Wo áljẹbrà.
  155. Braham R, Dawson B, Goodman C. Ipa ti afikun glucosamine lori awọn eniyan ti o ni iriri irora orokun deede. Br J Idaraya Med 2003; 37: 45-9. Wo áljẹbrà.
  156. Scroggie DA, Albright A, Harris MD. Ipa ti afikun glycosamine-chondroitin lori awọn ipele hemoglobin glycosylated ni awọn alaisan pẹlu iru ọgbẹ 2 mellitus: iṣakoso ibi-iṣakoso, afọju meji, iwadii ile-iwosan alailẹgbẹ. Arch Intern Med 2003; 163: 1587-90. Wo áljẹbrà.
  157. Richy F, Bruyere O, Ethgen O, et al. Ipilẹ ati ipa aisan ti glucosamine ati chondroitin ni osteoarthritis orokun: igbekale meta-onínọmbà. Arch Intern Med 2003; 163: 1514-22. Wo áljẹbrà.
  158. Salvatore S, Heuschkel R, Tomlin S, et al. Iwadii awakọ ti N-acetyl glucosamine, sobusitireti ti ijẹẹmu fun isopọmọ glycosaminoglycan, ni arun ọmọ inu onibaje onibaje onibaje. Aliment Pharmacol Ther 2000; 14: 1567-79 .. Wo áljẹbrà.
  159. Tallia AF, Cardone DA. Ilọ ikọ-fèé ti o ni nkan ṣe pẹlu afikun glucosamine-chondroitin. J Am Board Fam Pract 2002; 15: 481-4 .. Wo áljẹbrà.
  160. Tiku ML, Narla H, Karry SK, et al. Glucosamine Dena Ifarahan Lipoxidation Ilọsiwaju ati Iyipada Kemikali ti Lipoproteins nipasẹ Scavenging Reactive Carbonyl Intermediates. American College of Rheumatology Ipade; Oṣu Kẹwa 25-29, 2002. Afoyemọ 11.
  161. Alvarez-Soria MA, Largo R, Diez-Ortego E, et al. Glucosamine Dẹkun Iṣiṣẹ NF-kappa B ti IL-1ß ti o ni ifilọlẹ ni Awọn chondrocytes Osteoarthritic Eniyan. American College of Rheumatology Ipade; Oṣu Kẹwa 25-29, 2002. Afoyemọ 118.
  162. Ganu VA, Hu SI, Strassman J, et al. Awọn onigbọwọ ti N-glycosylation Dinku iṣelọpọ ti Cytokine ti iṣelọpọ Matrix Metalloproteinases, Nitric oxide, ati PGE2 lati Awọn Akọsilẹ Chondrocytes: Ẹrọ-iṣẹ Oludije fun Awọn ipa Chondroprotective ti d-Glucosamine. American College of Rheumatology Ipade; Oṣu Kẹwa 25-29, 2002. Afoyemọ 616.
  163. Du XL, Edelstein D, Dimmeler S, et al. Hyperglycemia ṣe idiwọ iṣẹ ṣiṣe nitric oxide synthase endothelial nipasẹ iyipada ifiweranṣẹ-itumọ ni aaye Akt. J Ile-iwosan Nawo 2001; 108: 1341-8. Wo áljẹbrà.
  164. Pavelka K, Gatterova J, Olejarova M, et al. Lilo imi-ọjọ Glucosamine ati idaduro ti ilọsiwaju ti osteoarthritis orokun: Ọdun 3 kan, ti a sọtọ, iṣakoso ibibo, iwadi afọju meji. Arch Intern Med 2002; 162: 2113-23. Wo áljẹbrà.
  165. Adebowale AO, Cox DS, Liang Z, et al. Onínọmbà ti glucosamine ati akoonu imi-ọjọ chondroitin ninu awọn ọja ti o ta ọja ati ifa Caco-2 ti awọn ohun elo aise imi-ọjọ chondroitin. JANA 2000; 3: 37-44.
  166. Bagasra O, Whittle P, Heins B, Pomerantz RJ. Iṣẹ ọlọjẹ alailowaya eniyan ti o jẹ iru iṣẹ 1 ti awọn monosaccharides ti imi-ọjọ: afiwe pẹlu awọn polysaccharides ti a ni imi ati awọn polyions miiran. J Infect Dis 1991; 164: 1082-90. Wo áljẹbrà.
  167. Nowak A, Szczesniak L, Rychlewski T, et al. Awọn ipele Glucosamine ninu awọn eniyan ti o ni arun inu ọkan pẹlu ati laisi iru ọgbẹ II. Pol Arch Med Wewn 1998; 100: 419-25. Wo áljẹbrà.
  168. Olszewski AJ, Szostak WB, McCully KS. Plasma glucosamine ati galactosamine ninu arun inu ọkan ara. Atherosclerosis 1990; 82: 75-83. Wo áljẹbrà.
  169. Yun J, Tomida A, Nagata K, Tsuruo T. Glucose ti o ṣe ilana ilana tẹnumọ fifun resistance si VP-16 ninu awọn sẹẹli akàn eniyan nipasẹ ikasi idinku ti DNA topoisomerase II. Oncol Res 1995; 7: 583-90. Wo áljẹbrà.
  170. Pouwels MJ, Jacobs JR, Span PN, ati al. Idapo glucosamine igba kukuru ko ni ipa ifamọ insulini ninu eniyan. J Clin Endocrinol Metab 2001; 86: 2099-103. Wo áljẹbrà.
  171. Monauni T, Zenti MG, Cretti A, et al. Awọn ipa ti idapo glucosamine lori yomijade insulini ati iṣẹ isulini ninu eniyan. Àtọgbẹ 2000; 49: 926-35. Wo áljẹbrà.
  172. Das A Jr, Hammad TA. Agbara ti apapo FCHG49 glucosamine hydrochloride, TRH122 iwuwo molikula kekere iṣuu soda chondroitin imi-ọjọ ati manganese ascorbate ninu iṣakoso ti osteoarthritis orokun. Ẹrọ kerekere ti Osteoarthritis 2000; 8: 343-50. Wo áljẹbrà.
  173. Igbimọ Ounje ati Ounjẹ, Institute of Medicine. Awọn Ifiweranṣẹ Ounjẹ fun Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Ejò, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, ati Zinc. Washington, DC: National Academy Press, 2002. Wa ni: www.nap.edu/books/0309072794/html/.
  174. Njẹ glucosamine ṣe alekun awọn ipele ọra inu ara ati titẹ ẹjẹ? Pharmacist’s Letter / Prescriber’s Letter 2001; 17: 171115.
  175. Reginster JY, Deroisy R, Rovati LC, et al. Awọn ipa-igba pipẹ ti imi-ọjọ glucosamine lori lilọsiwaju osteoarthritis: idanimọ, idanimọ iṣakoso ibibo. Lancet 2001; 357: 251-6. Wo áljẹbrà.
  176. Almada A, Harvey P, Platt K. Awọn ipa ti imi-ọjọ glycosamine imi-ọjọ lori itọka resistance insulin fast (FIRI) ni awọn eniyan ti ko ni dayabetik. FASEB J 2000; 14: A750.
  177. Leffler CT, Philippi AF, Leffler SG, ati al. Glucosamine, chondroitin, ati ascorbate manganese fun arun apapọ ti degenerative ti orokun tabi ẹhin kekere: aifọwọyi, afọju meji, iwadi awaoko-iṣakoso ibibo. Mil Med 1999; 164: 85-91. Wo áljẹbrà.
  178. Thie NM, Prasad NG, PW pataki. Igbelewọn ti imi-ọjọ glucosamine ti a fiwe si ibuprofen fun itọju ti isẹpo osteoarthritis apapọ akoko: afọju meji alaileto kan ti o ṣakoso iwadii iwosan oṣu mẹta 3. J Rheumatol 2001; 28: 1347-55. Wo áljẹbrà.
  179. Shankar RR, Zhu JS, Baron AD. Idapo Glucosamine ninu awọn eku ṣe afihan aiṣedede beta-sẹẹli ti mellitus mellitus ti o gbẹkẹle insulini. Iṣelọpọ 1998; 47: 573-7. Wo áljẹbrà.
  180. Rossetti L, Hawkins M, Chen W, ati al. Ni idapo idapọmọra glucosamine n fa ifilọ insulini ni normoglycemic ṣugbọn kii ṣe ni awọn eku ti o mọ nipa hyperglycemic. J Ile-iwosan Nawo 1995; 96: 132-40. Wo áljẹbrà.
  181. Burton AF, Anderson FH. Idinku idapọ ti 14C-glucosamine ibatan si 3H-N-acetyl glucosamine ninu iṣan inu ti awọn alaisan ti o ni arun inu. Am J Gastroenterol 1983; 78: 19-22. Wo áljẹbrà.
  182. Barclay TS, Tsourounis C, McCart GM. Glucosamine. Ann Pharmacother 1998; 32: 574-9. Wo áljẹbrà.
  183. Setnikar I, Palumbo R, Canali S, et al. Pharmacokinetics ti glucosamine ninu eniyan. Arzneimittelforschung 1993; 43: 1109-13. Wo áljẹbrà.
  184. Forster K, Schmid K, Rovati L, et al. Itọju igba pipẹ ti irẹlẹ-si-dede osteoarthritis ti orokun pẹlu imi-ọjọ glucosamine- iṣakoso ti a sọtọ, iwadi ile-afọju afọju meji. Eur J Clin Pharmacol 1996; 50: 542.
  185. Reichelt A. Agbara ati ailewu ti imi-ọjọ glucosamine imi-ọjọ ni osteoarthritis ti orokun. Iṣiro, iṣakoso ibi-aye, iwadi afọju afọju. Arzneimittelforschung 1994; 44: 75-80. Wo áljẹbrà.
  186. Qiu GX, Gao SN, Giacovelli G, et al. Agbara ati ailewu ti imi-ọjọ glucosamine dipo ibuprofen ni awọn alaisan pẹlu orokun osteoarthritis. Arzneimittelforschung 1998; 48: 469-74. Wo áljẹbrà.
  187. Pujalte JM, Llavore EP, Ylescupidez FR. Iyẹwo iwosan afọju meji ti imun-ara glycosamine sulphate ni itọju ipilẹ ti osteoarthrosis. Opin Iṣeduro Curr 1980; 7: 110-4. Wo áljẹbrà.
  188. Lopes Vaz A. Afọju afọju meji, imọ-iwosan ti ipa ojulumo ti ibuprofen ati glucosamine sulphate ni iṣakoso ti osteoarthrosis ti orokun ni awọn alaisan ti njade. Opin Med Res Opin 1982; 8: 145-9. Wo áljẹbrà.
  189. da Camara CC, Dowless GV. Imu imi-ọjọ Glucosamine fun osteoarthritis. Ann Pharmacother 1998; 32: 580-7. Wo áljẹbrà.
  190. Drovanti A, Bignamini AA, Rovati AL. Iṣẹ itọju ti imi-ọjọ imi-ọjọ glucosamine ni osteoarthrosis: iwadii afọju afọju-iṣakoso ibi-iṣakoso. Iwosan Ther 1980; 3: 260-72. Wo áljẹbrà.
  191. McAlindon TE, MP LaValley, Gulin JP, Felson DT. Glucosamine ati chondroitin fun itọju ti osteoarthritis: igbelewọn didara eleto ati igbekale apẹẹrẹ. JAMA 2000; 283: 1469-75. Wo áljẹbrà.
  192. Houpt JB, McMillan R, Wein C, Paget-Dellio SD. Ipa ti hydrochloride glucosamine ni itọju ti irora ti osteoarthritis ti orokun. J Rheumatol 1999; 26: 2423-30. Wo áljẹbrà.
  193. Rindone JP, Hiller D, Collacott E, et al. Aileto, idanwo ti iṣakoso ti glucosamine fun atọju osteoarthritis ti orokun. Oorun J Med 2000; 172: 91-4. Wo áljẹbrà.
  194. Foerster KK, Schmid K, Rovati LC. Imudara ti imi-ọjọ glucosamine ni osteoarthritis ti ẹhin lumbar: iṣakoso ibi-iṣakoso, iṣeduro, iwadi afọju meji. Am Coll Rheumatol 64th Ann Scientific Mtg, Philadelphia, PA: 2000; Oṣu Kẹwa 29- Oṣu kọkanla 2: áljẹbrà 1613.
  195. Kim YB, Zhu JS, Zierath JR, ati al. Idapo Glucosamine ninu awọn eku nyara idibajẹ isulini ti phosphoinositide 3-kinase ṣugbọn ko ṣe iyipada ifilọlẹ ti Akt / protein kinase B ninu iṣan ara. Àtọgbẹ 1999; 48: 310-20. Wo áljẹbrà.
  196. Holmang A, Nilsson C, Niklasson M, et al. Fifa ifunni insulin resistance nipasẹ glucosamine dinku sisan ẹjẹ ṣugbọn kii ṣe awọn ipele ti aarin ti boya glucose tabi insulini. Àtọgbẹ 1999; 48: 106-11. Wo áljẹbrà.
  197. Giaccari A, Morviducci L, Zorretta D, et al. Ni awọn ipa inu vivo ti glucosamine lori ifunjade insulini ati ifamọ insulin ninu eku: ibaramu to ṣee ṣe si awọn idahun aarun buburu si hyperglycaemia onibaje. Diabetologia 1995; 38: 518-24. Wo áljẹbrà.
  198. Balkan B, Dunning BE. Glucosamine ṣe idiwọ glucokinase ni vitro o si ṣe aipe aipe-glucose kan pato ti ifasilẹ insulin ni vivo ninu awọn eku. Àtọgbẹ 1994; 43: 1173-9. Wo áljẹbrà.
  199. Adams MI. Hype nipa glucosamine. Lancet 1999; 354: 353-4. Wo áljẹbrà.
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