Onkọwe Ọkunrin: Joan Hall
ỌJọ Ti ẸDa: 25 OṣU Keji 2021
ỌJọ ImudojuiwọN: 24 OṣU KẹFa 2024
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2/3 - Biomarkers of Immune Dysfunction | El Paso, Tx (2021)
Fidio: 2/3 - Biomarkers of Immune Dysfunction | El Paso, Tx (2021)

Akoonu

Kini idanwo alatako CCP?

Idanwo yii n wa CCP (peptide citrullinated peptide) awọn ara inu ẹjẹ. Awọn ara inu ara CCP, ti a tun pe ni awọn egboogi-egboogi-CCP, jẹ iru agboguntaisan ti a pe ni autoantibodies. Awọn egboogi-ara ati awọn ara-ara jẹ awọn ọlọjẹ ti a ṣe nipasẹ eto alaabo. Awọn egboogi ṣe aabo fun ọ lati aisan nipa ija awọn nkan ajeji bi awọn ọlọjẹ ati awọn kokoro arun. Awọn ẹya ara ẹni le fa arun nipasẹ kolu awọn sẹẹli ilera ti ara nipasẹ aṣiṣe.

Awọn egboogi CCP fojusi awọn awọ ara ilera ni awọn isẹpo. Ti a ba rii awọn egboogi CCP ninu ẹjẹ rẹ, o le jẹ ami ti arthritis rheumatoid. Arthritis Rheumatoid jẹ ilọsiwaju, arun autoimmune ti o fa irora, wiwu, ati lile ni awọn isẹpo. Awọn egboogi CCP ni a rii ni diẹ sii ju 75 ida ọgọrun eniyan ti o ni arthritis rheumatoid. Wọn ko fẹrẹ ri ninu awọn eniyan ti ko ni arun na.

Awọn orukọ miiran: Cyplic citrullinated peptide agboguntaisan, egboogi peptide antiitrullinated antitrullinated, agboguntaisan citrulline, peptide alatako-cyclic citrullinated, antibody CCP, ACPA


Kini o ti lo fun?

Ayẹwo antibody CCP kan ni a lo lati ṣe iranlọwọ iwadii aisan arthritis rheumatoid. Nigbagbogbo a ṣe pẹlu tabi lẹhin idanwo ifosiwewe rheumatoid (RF). Awọn okunfa Rheumatoid jẹ oriṣi miiran ti ara ẹni. Awọn idanwo RF ti a lo lati jẹ idanwo akọkọ lati ṣe iranlọwọ iwadii arthritis rheumatoid. Ṣugbọn awọn ifosiwewe RF ni a le rii ni awọn eniyan ti o ni awọn aarun autoimmune miiran ati paapaa ni diẹ ninu awọn eniyan ilera. Ọpọlọpọ awọn ijinlẹ ti fihan pe awọn ara inu ara CCP n pese ayẹwo ti o peye julọ ti arthritis rheumatoid ti a fiwewe pẹlu idanwo RF.

Kini idi ti Mo nilo idanwo alatako CCP?

O le nilo idanwo yii ti o ba ni awọn aami aiṣan ti arthritis rheumatoid. Iwọnyi pẹlu:

  • Apapọ apapọ
  • Agbara lile, paapaa ni owurọ
  • Wiwu apapọ
  • Rirẹ
  • Iba-kekere-kekere

O tun le nilo idanwo yii ti awọn idanwo miiran ko ba le jẹrisi tabi ṣe akoso idanimọ ti arthritis rheumatoid.

Kini o ṣẹlẹ lakoko idanwo alatako CCP?

Onimọṣẹ ilera kan yoo mu ayẹwo ẹjẹ lati iṣọn kan ni apa rẹ, ni lilo abẹrẹ kekere kan. Lẹhin ti a fi sii abẹrẹ, iye ẹjẹ kekere yoo gba sinu tube idanwo tabi igo kan. O le ni irọra diẹ nigbati abẹrẹ ba wọ inu tabi jade. Eyi maa n gba to iṣẹju marun.


Ṣe Mo nilo lati ṣe ohunkohun lati mura fun idanwo naa?

Rii daju lati sọ fun olupese ilera rẹ nipa gbogbo awọn oogun, awọn vitamin, ati awọn afikun awọn ounjẹ ti o mu. O le nilo lati da gbigba awọn nkan kan fun wakati 8 ṣaaju idanwo rẹ.

Ṣe eyikeyi awọn eewu si idanwo naa?

Ewu pupọ wa si nini idanwo ẹjẹ. O le ni irora diẹ tabi ọgbẹ ni aaye ibiti a ti fi abẹrẹ sii, ṣugbọn ọpọlọpọ awọn aami aisan lọ ni kiakia.

Kini awọn abajade tumọ si?

Ti awọn abajade agboguntaisan CCP rẹ jẹ rere, o tumọ si pe a rii awọn ara inu ara rẹ ninu ẹjẹ rẹ. Abajade odi ko tumọ si pe a ko rii awọn ara inu ara CCP. Itumọ awọn abajade wọnyi le dale lori awọn abajade ti idanimọ ifosiwewe rheumatoid (RF) gẹgẹbi idanwo ti ara.

Ti o ba ni awọn aami aiṣan ti arthritis rheumatoid, ati pe awọn abajade rẹ fihan:

  • Awọn ara inu ara CCP ti o dara ati RF rere, o ṣee ṣe tumọ si pe o ni arthritis rheumatoid.
  • Awọn ara inu ara CCP ti o dara ati RF odi, o le tumọ si pe o wa ni awọn ipele ibẹrẹ ti arthritis rheumatoid tabi yoo dagbasoke ni ọjọ iwaju.
  • Awọn egboogi ara CCP ti ko ni odi ati RF odi, o tumọ si pe o ṣeeṣe ki o ni arthritis rheumatoid. Olupese rẹ le nilo lati ṣe awọn idanwo diẹ sii lati ṣe iranlọwọ lati wa ohun ti o fa awọn aami aisan rẹ.

Kọ ẹkọ diẹ sii nipa awọn idanwo yàrá, awọn sakani itọkasi, ati oye awọn abajade.


Njẹ ohunkohun miiran ti Mo nilo lati mọ nipa idanwo alatako CCP kan?

Arthritis Rheumatoid le nira lati ṣe iwadii, paapaa ni awọn ipele ibẹrẹ rẹ. Olupese rẹ le paṣẹ ọkan tabi diẹ awọn idanwo ni afikun si agboguntaisan CCP ati awọn idanwo RF. Iwọnyi pẹlu awọn egungun-x ti awọn isẹpo rẹ ati awọn ayẹwo ẹjẹ wọnyi:

  • Oṣuwọn erofo ara Erythrocyte (ESR)
  • Onínọmbà iṣan omi Synovial
  • Amuaradagba C-ifaseyin
  • Antinuclear agboguntaisan

Awọn idanwo ẹjẹ wọnyi le fihan awọn ami ti igbona. Iredodo jẹ iru idaamu eto eto. O le jẹ aami aisan ti arthritis rheumatoid.

Awọn itọkasi

  1. Abdul Wahab A, Mohammad M, Rahman MM, Mohamed Said MS. Egboogi peptide citrullinated citrullinated anti-cyclic jẹ itọka ti o dara fun ayẹwo ti arthritis rheumatoid. Pak J Med Sci. 2013 May-Jun [ti a tọka si 2020 Feb 12]; 29 (3): 773-77. Wa lati: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809312
  2. Ile-ẹkọ giga ti Amẹrika ti Rheumatology [Intanẹẹti]. Atlanta: Ile-ẹkọ giga ti Amẹrika ti Rheumatology; c2020. Gilosari: Igbeyewo agboguntaisan CCP citrullinated peptide (CCP); [tọka si 2020 Feb 12]; [nipa iboju 3]. Wa lati: https://www.rheumatology.org/Learning-Center/Glossary/ArticleType/ArticleView/ArticleID/439
  3. Arthritis Foundation [Intanẹẹti]. Atlanta: Arthritis Foundation; Arthritis Rheumatoid; [tọka si 2020 Feb 12]; [nipa iboju 3]. Wa lati: https://www.arthritis.org/diseases/rheumatoid-arthritis
  4. Ile-iwosan Cleveland [Intanẹẹti]. Cleveland (OH): Ile-iwosan Cleveland; c2020. Arthritis Rheumatoid: Ayẹwo ati Awọn idanwo; [toka si 2020 Feb 12]; [nipa iboju 4]. Wa lati: https://my.clevelandclinic.org/health/diseases/4924-rheumatoid-arthritis/diagnosis-and-tests
  5. Familydoctor.org [Intanẹẹti]. Leawood (KS): Ile ẹkọ giga ti Amẹrika ti Awọn Onisegun Ẹbi; c2020. Arthritis Rheumatoid; [imudojuiwọn 2018 Aug 28; tọka si 2020 Feb 12]; [nipa iboju 3]. Wa lati: https://familydoctor.org/condition/rheumatoid-arthritis
  6. HSS [Intanẹẹti]. New York: Ile-iwosan fun Isẹ abẹ Pataki; c2019. Iyeyeye Awọn idanwo Lab ati Arthur Rheumatoid Arthritis; [imudojuiwọn 2018 Mar 26; tọka si 2020 Feb 12]; [nipa iboju 4]. Wa lati: https://www.hss.edu/conditions_understanding-rheumatoid-arthritis-lab-tests-results.asp
  7. Awọn idanwo Lab lori Ayelujara [Intanẹẹti]. Washington DC: Association Amẹrika fun Kemistri Iṣoogun; c2001–2020. Awọn ẹya ara ẹrọ; [imudojuiwọn 2019 Nov 13; tọka si 2020 Feb 12]; [nipa iboju 3]. Wa lati: https://labtestsonline.org/tests/autoantibodies
  8. Awọn idanwo Lab lori Ayelujara [Intanẹẹti]. Washington DC: Association Amẹrika fun Kemistri Iṣoogun; c2001–2020. Cyclic Citrullinated Peptide Antibody; [imudojuiwọn 2019 Dec 24; tọka si 2020 Feb 12]; [nipa iboju 2]. Wa lati: https://labtestsonline.org/tests/cyclic-citrullinated-peptide-antibody
  9. Awọn idanwo Lab lori Ayelujara [Intanẹẹti]. Washington DC: Association Amẹrika fun Kemistri Iṣoogun; c2001–2020. Iredodo; [imudojuiwọn 2017 Jul 10; tọka si 2020 Feb 12]; [nipa iboju 3]. Wa lati: https://labtestsonline.org/glossary/inflammation
  10. Awọn idanwo Lab lori Ayelujara [Intanẹẹti]. Washington DC: Association Amẹrika fun Kemistri Iṣoogun; c2001–2020. Okunfa Rheumatoid (RF); [imudojuiwọn 2020 Jan 13; tọka si 2020 Feb 12]; [nipa iboju 2]. Wa lati: https://labtestsonline.org/tests/rheumatoid-factor-rf
  11. Ile-iwosan Mayo [Intanẹẹti]. Foundation Mayo fun Ẹkọ Iṣoogun ati Iwadi; c1998–2020. Arthritis Rheumatoid: Ayẹwo ati itọju; 2019 Mar 1 [ti a tọka si 2020 Feb 12]; [nipa iboju 4]. Wa lati: https://www.mayoclinic.org/diseases-conditions/rheumatoid-arthritis/diagnosis-treatment/drc-20353653
  12. Awọn ile-iwosan Ile-iwosan Mayo [Intanẹẹti]. Foundation Mayo fun Ẹkọ Iṣoogun ati Iwadi; c1995–2020. Idanwo CCP: Awọn Antibodies Peptide Citrullinated, IgG, Omi ara: Ile-iwosan ati Itumọ; [tọka si 2020 Feb 12]; [nipa iboju 2]. Wa lati: https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/84182
  13. Ẹya Olumulo Afowoyi Merck [Intanẹẹti]. Kenilworth (NJ): Merck & Co. Inc.; c2020. Arthritis Rheumatoid (RA); 2019 Feb [ti a tọka si 2020 Feb 12]; [nipa iboju 2]. Wa lati: https://www.merckmanuals.com/home/bone,-joint,-and-muscle-disorders/joint-disorders/rheumatoid-arthritis-ra
  14. Okan Orilẹ-ede, Ẹdọfóró, ati Ẹjẹ Ẹjẹ [Intanẹẹti]. Bethesda (MD): Ẹka Ilera ti U.S. ati Awọn Iṣẹ Eda Eniyan; Awọn idanwo ẹjẹ; [tọka si 2020 Feb 12]; [nipa iboju 3]. Wa lati: https://www.nhlbi.nih.gov/health-topics/blood-tests
  15. Arthritis Rheumatoid: Nẹtiwọọki Atilẹyin Arthritis Atilẹyin Rheumatoid [Intanẹẹti]. Orlando (FL): Nẹtiwọọki Atilẹyin Arthritis Rheumatoid Arthritis; RA ati Anti-CCP: Kini Idi ti idanwo Anti-CCP?; 2018 Oṣu Kẹwa 27 [ti a tọka si 2020 Feb 12]; [nipa iboju 3]. Wa lati: https://www.rheumatoidarthritis.org/ra/diagnosis/anti-ccp
  16. Yunifasiti ti Rochester Medical Center [Intanẹẹti]. Rochester (NY): Yunifasiti ti Ile-iṣẹ Iṣoogun ti Rochester; c2020. Encyclopedia Health: CCP; [toka si 2020 Feb 12]; [nipa iboju 2]. Wa lati: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=ccp

Alaye lori aaye yii ko yẹ ki o lo bi aropo fun itọju iṣoogun ọjọgbọn tabi imọran. Kan si olupese ilera kan ti o ba ni awọn ibeere nipa ilera rẹ.

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