Atọka CSF Immunoglobulin G (IgG)

Akoonu

• Kini itọka CSF IgG kan?
• Kini o ti lo fun?
• Kini idi ti Mo nilo itọka CSF IgG kan?
• Kini o ṣẹlẹ lakoko itọka CSF IgG kan?
• Ṣe Mo nilo lati ṣe ohunkohun lati mura fun idanwo naa?
• Ṣe eyikeyi awọn eewu si idanwo naa?
• Kini awọn abajade tumọ si?
• Njẹ ohunkohun miiran ti Mo nilo lati mọ nipa itọka CSF IgG kan?
• Awọn itọkasi

Kini itọka CSF IgG kan?

CSF duro fun iṣan cerebrospinal. O jẹ omi ti o mọ, ti ko ni awọ ti o wa ninu ọpọlọ rẹ ati ọpa-ẹhin. Opolo ati ọpa-ẹhin ṣe eto aifọkanbalẹ aringbungbun rẹ. Eto iṣakoso aifọkanbalẹ rẹ n ṣakoso ati ipoidojuko ohun gbogbo ti o ṣe, pẹlu iṣọn ara iṣan, iṣẹ eto ara, ati paapaa ironu ati ero idiju.

IgG duro fun immunoglobulin G, iru egboogi kan. Awọn egboogi jẹ awọn ọlọjẹ ti eto aarun ṣe lati ja awọn ọlọjẹ, kokoro arun, ati awọn nkan ajeji miiran. Atọka CSF IgG ṣe iwọn awọn ipele ti IgG ninu iṣan ara iṣan ara rẹ. Awọn ipele giga ti IgG le tumọ si pe o ni aiṣedede autoimmune. Rudurudu autoimmune fa eto alaabo rẹ lati kọlu awọn sẹẹli ilera, awọn ara, ati / tabi awọn ara nipa aṣiṣe. Awọn rudurudu wọnyi le fa awọn iṣoro ilera to lewu.

Awọn orukọ miiran: Ipele IgG ti iṣan ara ọpọlọ, wiwọn IgG cerebrospinal, ipele CSF IgG, IgG (Immunoglobulin G) iṣan eegun eefun, oṣuwọn idapọ IgG

Kini o ti lo fun?

Atọka CSF IgG ni a lo lati ṣayẹwo fun awọn aisan ti eto aifọkanbalẹ aringbungbun. Nigbagbogbo a maa n lo lati ṣe iranlọwọ iwadii ọpọ sclerosis (MS). MS jẹ aiṣedede autoimmune onibaje ti o kan eto aifọkanbalẹ aringbungbun. Ọpọlọpọ eniyan ti o ni MS ni awọn aami aiṣedede pẹlu ailera pupọ, ailera, iṣoro nrin, ati awọn iṣoro iran. O to iwọn 80 fun awọn alaisan MS ni giga ju awọn ipele deede ti IgG.

Kini idi ti Mo nilo itọka CSF IgG kan?

O le nilo itọka CSF IgG ti o ba ni awọn aami aiṣan ti ọpọlọ-ọpọlọ pupọ (MS).

Awọn aami aisan ti MS pẹlu:

• Ti ko dara tabi iran meji
• Jije ni awọn apa, ese, tabi oju
• Awọn iṣan ara iṣan
• Awọn isan alailagbara
• Dizziness
• Awọn iṣoro iṣakoso àpòòtọ
• Ifamọ si imọlẹ
• Iran meji
• Awọn ayipada ninu ihuwasi
• Iruju

Kini o ṣẹlẹ lakoko itọka CSF IgG kan?

A o gba omi ara cerebrospinal rẹ nipasẹ ilana ti a pe ni tẹẹrẹ ẹhin, ti a tun mọ ni lilu lumbar. Ọpa eefun ni a maa n ṣe ni ile-iwosan kan. Lakoko ilana:

• Iwọ yoo dubulẹ ni ẹgbẹ rẹ tabi joko lori tabili idanwo.
• Olupese ilera kan yoo sọ ẹhin rẹ di mimọ ati ki o lo anesitetiki sinu awọ rẹ, nitorinaa iwọ kii yoo ni irora lakoko ilana naa. Olupese rẹ le fi ipara ipara kan sẹhin sẹhin ṣaaju abẹrẹ yii.
• Lọgan ti agbegbe ti o wa ni ẹhin rẹ ti parẹ patapata, olupese rẹ yoo fi sii abẹrẹ, abẹrẹ ṣofo laarin awọn eegun meji ni ẹhin kekere rẹ. Vertebrae ni awọn eegun kekere ti o ṣe ẹhin ẹhin rẹ.
• Olupese rẹ yoo yọ iye kekere ti omi ara ọpọlọ fun idanwo. Eyi yoo gba to iṣẹju marun.
• Iwọ yoo nilo lati duro gan-an lakoko ti a yọ omi kuro.
• Olupese rẹ le beere lọwọ rẹ lati dubulẹ lori ẹhin rẹ fun wakati kan tabi meji lẹhin ilana naa. Eyi le ṣe idiwọ fun ọ lati ni orififo lẹhinna.

Ṣe Mo nilo lati ṣe ohunkohun lati mura fun idanwo naa?

O ko nilo awọn ipese pataki eyikeyi fun itọka CSF IgG kan, ṣugbọn o le beere lọwọ rẹ lati sọ apo-inu ati inu rẹ di ofo ṣaaju idanwo naa.

Ṣe eyikeyi awọn eewu si idanwo naa?

Ewu pupọ wa si nini titẹ ọpa ẹhin. O le ni irọra kekere kan tabi titẹ nigbati o ba fi abẹrẹ sii. Lẹhin idanwo naa, o le ni orififo, ti a pe ni orififo post-lumbar. O fẹrẹ to ọkan ninu eniyan 10 yoo gba orififo post-lumbar. Eyi le ṣiṣe ni fun awọn wakati pupọ tabi to ọsẹ kan tabi diẹ sii. Ti o ba ni orififo ti o gun ju awọn wakati lọpọlọpọ lọ, ba olupese ilera rẹ sọrọ. Oun tabi obinrin le ni anfani lati pese itọju lati ṣe iyọda irora naa.

O le ni irọrun diẹ ninu irora tabi tutu ninu ẹhin rẹ ni aaye ti a ti fi abẹrẹ sii. O tun le ni diẹ ninu ẹjẹ ni aaye naa.

Kini awọn abajade tumọ si?

Ti itọka CSG IgG rẹ ba han ga ju awọn ipele deede lọ, o le tọka:

• Ọpọ sclerosis
• Arun autoimmune miiran, gẹgẹbi lupus tabi arthritis rheumatoid
• Aisan ailopin bi HIV tabi jedojedo
• Ọpọ myeloma, akàn kan ti o kan awọn sẹẹli ẹjẹ funfun

Ti itọka IgG rẹ ba fihan kekere ju awọn ipele deede, o le tọka:

• Rudurudu ti o sọ eto alaabo di alailera. Awọn rudurudu wọnyi jẹ ki o nira lati ja awọn akoran.

Ti awọn abajade atokọ IgG rẹ ko ba ṣe deede, o le ma tumọ si pe o ni ipo iṣoogun ti o nilo itọju. Awọn abajade le yatọ si da lori ọpọlọpọ awọn ifosiwewe pẹlu ọjọ ori rẹ ati ilera gbogbogbo, ati awọn oogun ti o n mu. Ti o ba ni awọn ibeere nipa awọn abajade rẹ, sọrọ si olupese iṣẹ ilera rẹ.

Kọ ẹkọ diẹ sii nipa awọn idanwo yàrá, awọn sakani itọkasi, ati oye awọn abajade.

Njẹ ohunkohun miiran ti Mo nilo lati mọ nipa itọka CSF IgG kan?

Atọka CSF IgG ni igbagbogbo lati ṣe iranlọwọ lati ṣe iwadii aisan ọpọlọ-ọpọlọ (MS), ṣugbọn kii ṣe pataki idanwo MS. Ko si idanwo kan ti o le sọ fun ọ boya o ni MS. Ti olupese ilera rẹ ba ro pe o ni MS, o ṣee ṣe ki o ni ọpọlọpọ awọn idanwo miiran lati jẹrisi tabi ṣe akoso idanimọ kan.

Lakoko ti ko si imularada fun MS, ọpọlọpọ awọn itọju wa ti o le ṣe iranlọwọ lati ṣe iranlọwọ awọn aami aisan ati fa fifalẹ ilọsiwaju ti arun na.

Awọn itọkasi

1. Ilera Allina [Intanẹẹti]. Minneapolis: Ilera Allina; Iwọn IgG ti Cerebrospinal fluid, pipọ; [tọka si 2020 Jan 1]; [nipa iboju 3]. Wa lati: https://account.allinahealth.org/library/content/49/150438
2. Johns Hopkins Oogun [Intanẹẹti]. Ile-ẹkọ giga Johns Hopkins; c2020. Ilera: Awọn aipe IgG; [tọka si 2020 Jan 1]; [nipa iboju 3]. Wa lati: https://www.hopkinsmedicine.org/health/conditions-and-diseases/igg-deficiencies
3. Johns Hopkins Oogun [Intanẹẹti]. Ile-ẹkọ giga Johns Hopkins; c2020. Ilera: Lumbar Puncture; [tọka si 2020 Jan 1]; [nipa iboju 3]. Wa lati: https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/lumbar-puncture
4. Awọn idanwo Lab lori Ayelujara [Intanẹẹti]. Washington D.C.; Ẹgbẹ Amẹrika fun Kemistri Iwosan; c2001–2018. Awọn Arun Autoimmune; [imudojuiwọn 2017 Oṣu Kẹwa 10; toka si 2018 Jan 13]; [nipa iboju 3]. Wa lati: https://labtestsonline.org/conditions/autoimmune-diseases
5. Awọn idanwo Lab lori Ayelujara [Intanẹẹti]. Washington D.C.; Ẹgbẹ Amẹrika fun Kemistri Iwosan; c2001–2020. Idanwo Fluid Cerebrospinal (CSF); [imudojuiwọn 2019 Dec 24; tọka si 2020 Jan 1]; [nipa iboju 2]. Wa lati: https://labtestsonline.org/tests/cerebrospinal-fluid-csf-analysis
6. Awọn idanwo Lab lori Ayelujara [Intanẹẹti]. Washington D.C.; Ẹgbẹ Amẹrika fun Kemistri Iwosan; c2001–2018. Ọpọ Sclerosis; [imudojuiwọn 2017 Oṣu Kẹwa 10; toka si 2018 Jan 13]; [nipa iboju 3]. Wa lati: https://labtestsonline.org/conditions/multiple-sclerosis
7. Ile-iwosan Mayo: Awọn ile-iwosan Iṣoogun Mayo [Intanẹẹti]. Foundation Mayo fun Ẹkọ Iṣoogun ati Iwadi; c1995–2018. Idanwo Idanwo: SFIN: Itan IgG Cerebrospinal (CSF); [toka si 2018 Jan 13]; [nipa iboju 4]. Wa lati: https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/8009
8. Ẹya Olumulo Afowoyi Merck [Intanẹẹti]. Kenilworth (NJ): Merck & Co. Inc.; c2018. Awọn idanwo fun Ọpọlọ, Okun-ọpa-ẹhin, ati Awọn Ẹjẹ Nerve [ti a tọka si 2018 Jan 13]; [nipa iboju 2]. Wa lati: http://www.merckmanuals.com/home/brain,-spinal-cord,-and-nerve-disorders/diagnosis-of-brain,-spinal-cord,-and-nerve-disorders/tests-for -ọpọlọ, -ẹgbẹ-okun, -ati awọn iṣọn-ara-ara
9. National Cancer Institute [Intanẹẹti]. Bethesda (MD): Ẹka Ilera ti U.S. ati Awọn Iṣẹ Eda Eniyan; NCI Dictionary ti Awọn ofin akàn: ọpọ myeloma [ti a tọka si 2018 Jan 13]; [nipa iboju 3]. Wa lati: https://www.cancer.gov/publications/dictionaries/cancer-terms?cdrid=4579
10. National Institute of Neurological Disorders and Stroke [Intanẹẹti]. Bethesda (MD): Ẹka Ilera ti U.S. ati Awọn Iṣẹ Eda Eniyan; Ọpọ Sclerosis: Ireti Nipasẹ Iwadi; [toka si 2018 Jan 13]; [nipa iboju 3]. Wa lati: https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Hope-Through-Research/Multiple-Sclerosis-Hope-Through-Research#3215_4
11. National Multiple Sclerosis Society [Intanẹẹti]. National Multiple Sclerosis Society; Ṣiṣe ayẹwo MS; [toka si 2018 Jan 13]; [nipa iboju 3]. Wa lati: https://www.nationalmssociety.org/Symptoms-Diagnosis/Diagnosing-MS
12. National Multiple Sclerosis Society [Intanẹẹti]. National Multiple Sclerosis Society; Awọn aami aisan MS; [toka si 2018 Jan 13]; [nipa iboju 4]. Wa lati: https://www.nationalmssociety.org/Symptoms-Diagnosis/MS-Symptoms
13. NIH U.S. Library of Medicine: Itọkasi Itọkasi Ile Jiini [Intanẹẹti]. Bethesda (MD): Ẹka Ilera ti U.S. ati Awọn Iṣẹ Eda Eniyan; Ọpọ Sclerosis; 2018 Jan 9 [tọka si 2018 Jan 13]; [nipa iboju 3]. Wa lati: https://ghr.nlm.nih.gov/condition/multiple-sclerosis
14. Yunifasiti ti Rochester Medical Center [Intanẹẹti]. Rochester (NY): Yunifasiti ti Ile-iṣẹ Iṣoogun ti Rochester; c2018. Encyclopedia Health: Pipo Immunoglobulins; [toka si 2018 Jan 13]; [nipa iboju 2]. Wa lati: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=quantitative_immunoglobulins
15. Yunifasiti ti Rochester Medical Center [Intanẹẹti]. Rochester (NY): Yunifasiti ti Ile-iṣẹ Iṣoogun ti Rochester; c2020. Encyclopedia Health: Tẹ ni kia kia ẹhin (Lumbar Puncture) fun Awọn ọmọde; [tọka si 2020 Jan 1]; [nipa iboju 2]. Wa lati: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid=P02625
16. Ilera UW [Intanẹẹti]. Madison (WI): Ile-ẹkọ giga ti Wisconsin Awọn ile-iwosan ati Alaṣẹ Ile-iwosan; c2018. Immunoglobulins: Akopọ Idanwo; [imudojuiwọn 2017 Oṣu Kẹwa 9; toka si 2018 Jan 13]; [nipa iboju 2]. Wa lati: https://www.uwhealth.org/health/topic/medicaltest/immunoglobulins/hw41342.html
17. Ilera UW [Intanẹẹti]. Madison (WI): Ile-ẹkọ giga ti Wisconsin Awọn ile-iwosan ati Alaṣẹ Ile-iwosan; c2018. Immunoglobulins: Awọn abajade; [imudojuiwọn 2017 Oṣu Kẹwa 9; toka si 2018 Jan 13]; [nipa awọn iboju 8]. Wa lati: https://www.uwhealth.org/health/topic/medicaltest/immunoglobulins/hw41342.html#hw41354

Alaye lori aaye yii ko yẹ ki o lo bi aropo fun itọju iṣoogun ọjọgbọn tabi imọran. Kan si olupese ilera kan ti o ba ni awọn ibeere nipa ilera rẹ.